Phosphonic diamide, pentamethyl-

Base Information

• Chemical Name: Phosphonic diamide, pentamethyl-
• CAS No.: 2511-17-3
• Molecular Formula: C5H15 N2 O P
• Molecular Weight: 150.161
• European Community (EC) Number: 219-728-7
• NSC Number: 133862
• UNII: 5TNF8HB4BF
• DSSTox Substance ID: DTXSID50179795
• Nikkaji Number: J192.001D
• Wikidata: Q83050311
• Mol file: 2511-17-3.mol

Synonyms:2511-17-3;Phosphonic diamide, pentamethyl-;METHYLPHOSPHONIC BIS(DIMETHYLAMIDE);Pentamethylphosphonic diamide;N-[dimethylamino(methyl)phosphoryl]-N-methylmethanamine;EINECS 219-728-7;5TNF8HB4BF;AI3-62676;NSC-133862;NSC133862;UNII-5TNF8HB4BF;C5H15N2OP;SCHEMBL115308;DTXSID50179795;C5-H15-N2-O-P;methyl phosphonic bis(dimethylamide);Methylphosphonic bis-(dimethylamide);MFCD00015433;Methylbis(dimethylamino)phosphine oxide;N,N',N'-Tetramethylmethylphosphonamide;NSC 133862;methylphosphonic acid bis(di methylamide);METHYLPHOSPHONICBIS(DIMETHYLAMIDE);N,N,N',N'-Tetramethylmethylphosphonamide;Methanephosphonic Acid-Bis-(Dimethylamide);N,N,N',N',p-Pentamethylphosphonic diamide;FT-0623062;N,N,N',N',p-Pentamethylphosphonic diamide #;N,N,N',N'-Tetramethyl methanephosphorodiamide;Phosphonic diamide, N,N,N',N',P-pentamethyl-;Phosphorodiamidous acid, tetramethyl-, methyl ester

Chemical Property of Phosphonic diamide, pentamethyl-

Chemical Property:

• Vapor Pressure: 1.22mmHg at 25°C
• Melting Point: -3.2 °C
• Refractive Index: 1.4590
• Boiling Point: 174.2°Cat760mmHg
• PKA: 3.92±0.70(Predicted)
• Flash Point: 59.2°C
• PSA: 33.36000
• Density: 1.002g/cm³
• LogP: 0.93250
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 150.09220010
• Heavy Atom Count: 9
• Complexity: 121

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-20/22
• Safety Statements: 36/37-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)P(=O)(C)N(C)C

Technology Process of Phosphonic diamide, pentamethyl-

There total 7 articles about Phosphonic diamide, pentamethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

methylphosphonic acid dichloroanhydride (676-97-1) + dimethyl amine (124-40-3) → pentamethylphosphonic diamide (2511-17-3)

Guidance literature:

With triethylamine; In benzene; for 24h;

Reference yield: 49.0%

chlorobis(dimethylamino)methylphosphonium iodide (75841-74-6) → pentamethylphosphonic diamide (2511-17-3)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 2h; Heating;

Reference yield: 45.0%

iodobenzene (591-50-4) + C10H28CuN4O2P2(1-)*Li(1+) → pentamethylphosphonic diamide (2511-17-3) + N,N,N',N'-tetramethyldiamide of phenylmethanephosphonic acid (14655-73-3) + C10H28N4O2P2

Guidance literature:

palladium diacetate; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; for 6h; Heating;

DOI:10.1023/A:1012326700328

upstream raw materials:

methylphosphonic acid dichloroanhydride

dimethyl amine

N,N,N,N,N,N-hexamethylphosphoric triamide

methyl bromide

Downstream raw materials:

N,N,N',N'-tetramethyldiamide of phenylmethanephosphonic acid

C₁₄H₁₅N₄OP

C₉H₁₃N₄OP

C₈H₁₁N₄OP

Refernces

• 1、 McIntosh, John M.,Pillon, Lilianna, Z.. "Dihydrothiophenes.10. The preparation and Diels-Alder reactions of some sulfur and phosphorus-substituted dienophiles and 2-aza-substituted 1,3-dienes". . p. 2089 - 2093. Retrieved 2007/10/02.
• 2、 Gorbatenko, Zh. K.,Mitel'man, I. E.,Feshchenko, N. G.. "REACTIONS OF TETRAALKYLPHOSPHORODIAMIDOUS CHLORIDES WITH IODINE". . p. 1400 - 1403. Retrieved 2007/10/02.