Pentadecylamine

Base Information

• Chemical Name: Pentadecylamine
• CAS No.: 2570-26-5
• Molecular Formula: C15H33 N
• Molecular Weight: 227.434
• European Community (EC) Number: 219-912-7
• UN Number: 2923,3259
• UNII: 2F7N79M9VH
• DSSTox Substance ID: DTXSID8062529
• Nikkaji Number: J34.521K
• Wikidata: Q7164947
• Metabolomics Workbench ID: 71520
• ChEMBL ID: CHEMBL2036099
• Mol file: 2570-26-5.mol

Synonyms:pentadecylamine

Chemical Property of Pentadecylamine

Chemical Property:

• Vapor Pressure: 1 mm Hg ( 120.5 °C)
• Melting Point: 35-37oC(lit.)
• Refractive Index: 1.4480
• Boiling Point: 307.3°Cat760mmHg
• PKA: 10.61(at 25℃)
• Flash Point: 129.3°C
• PSA: 26.02000
• Density: 0.812g/cm³
• LogP: 5.73660
• Storage Temp.: 2-8°C
• Solubility.: soluble in Methanol
• XLogP3: 6.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 13
• Exact Mass: 227.261300057
• Heavy Atom Count: 16
• Complexity: 112
• Transport DOT Label: Corrosive Poison

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Aminopentadecane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 20/22-34
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CCCCCCCCCCCCCCCN

Technology Process of Pentadecylamine

There total 17 articles about Pentadecylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

heptadecan-2-one oxime + sulfuric acid (7664-93-9) + acetic acid (64-19-7,77671-22-8) → 1-pentadecylamine (2570-26-5) + 1-hexadecylcarboxylic acid (57-10-3)

Guidance literature:

und Verseifung mit alkoh.KOH;

Reference yield:

1-azidopentadecane (503629-61-6) → 1-pentadecylamine (2570-26-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 3h; Heating;

DOI:10.1021/jm0340795

Reference yield:

pentadecanol (629-76-5) → 1-pentadecylamine (2570-26-5)

Guidance literature:

Multi-step reaction with 3 steps

1: pyridine / 5 h / 20 °C

2: sodium azide / dimethylformamide / 90 °C

3: LiAlH₄ / diethyl ether / 3 h / Heating

With pyridine; lithium aluminium tetrahydride; sodium azide; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1021/jm0340795

upstream raw materials:

pentadecanenitrile

pentadecanyl isocyanate

pentadecyl-carbamic acid methyl ester

sodium methylate

Downstream raw materials:

2,5-Dimethyl-3,6-bis-pentadecylamino-[1,4]benzoquinone

2,5-Dimethoxy-3,6-bis-pentadecylamino-[1,4]benzoquinone

pentadecanoic acid[2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-yl]-amide

pentadecanyl isocyanate

Refernces

• 1、 Vandevoorde, Séverine,Tsuboi, Kazuhito,Ueda, Natsuo,Jonsson, Kent-Olov,Fowler, Christopher J.,Lambert, Didier M.. "Esters, retroesters, and a retroamide of palmitic acid: Pool for the first selective inhibitors of N-palmitoylethanolamine-selective acid amidase". . p. 4373 - 4376. Retrieved 2007/10/03.