20,26-dihydroxyecdysone

Base Information

• Chemical Name: 20,26-dihydroxyecdysone
• CAS No.: 19458-46-9
• Molecular Formula: C27H44 O8
• Molecular Weight: 496.642
• Mol file: 19458-46-9.mol

Synonyms:5b-Cholest-7-en-6-one, 2b,3b,14,20,22,25,26-heptahydroxy-, (22R)- (8CI);20,26-Dihydroxyecdysone; 26-Hydroxy-b-ecdysone; Podecdysone C

Chemical Property of 20,26-dihydroxyecdysone

Chemical Property:

• Vapor Pressure: 5.47E-26mmHg at 25°C
• Boiling Point: 750.4°Cat760mmHg
• PKA: 14.13±0.70(Predicted)
• Flash Point: 421.5°C
• PSA: 158.68000
• Density: 1.33g/cm³
• LogP: 0.82640

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 20,26-dihydroxyecdysone

There total 4 articles about 20,26-dihydroxyecdysone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ponasterone A (13408-48-5,19338-77-3,78148-78-4,13408-56-5) → 20-Hydroxyecdysone (5289-74-7) + inokosterone (88980-54-5) + 25-deoxy-20-hydroxyecdyson-26-oic acid (59971-16-3) + 20-hydroxyecdyson-26-oic acid (86583-58-6) + 20,26-dihydroxyecdysone (19458-46-9)

Guidance literature:

With air; D-glucose; epidermis of premolt crab Carcinus maenas L; penicillin G; 2-amino-2-hydroxymethyl-1,3-propanediol; monophenylthiourea; In water; at 20 ℃; for 48h; Mechanism; different metabolism after incubation of various tissues or injection in intermolt and premolt crabs (Carcinus maenas L_.), 3H labeled studies;

DOI:10.1016/0039-128X(84)90043-6

Reference yield:

ecdysone (3604-87-3) → 20-Hydroxyecdysone (5289-74-7) + 3-epi-26-hydroxyecdysone (75319-59-4) + 26-hydroxyecdysone (52717-49-4) + Coronatasterone (5289-74-7,7703-93-7,22678-71-3,22678-72-4,35241-82-8,84580-28-9,123238-67-5,54053-93-9) + 3-epi-20,26-dihydroxyecdysone (71939-17-8) + 20,26-dihydroxyecdysone (19458-46-9)

Guidance literature:

metabolism after injection into Pieris brassicae (Lepidoptera) pharate pupae, 3H labeled study;

DOI:10.1016/0039-128X(80)90018-5

Reference yield:

26-hydroxyecdysone (52717-49-4) → 20-Hydroxyecdysone (5289-74-7) + ecdysone (3604-87-3) + 3-epi-26-hydroxyecdysone (75319-59-4) + Coronatasterone (5289-74-7,7703-93-7,22678-71-3,22678-72-4,35241-82-8,84580-28-9,123238-67-5,54053-93-9) + 3-epi-20,26-dihydroxyecdysone (71939-17-8) + 20,26-dihydroxyecdysone (19458-46-9)

Guidance literature:

metabolism after injection into Pieris brassicae (Lepidoptera) pharate pupae, 3H labeled study;

DOI:10.1016/0039-128X(80)90018-5

upstream raw materials:

20-hydroxyecdysone 2,3:20,22-diacetonide

ecdysone

ponasterone A

26-hydroxyecdysone

Refernces

• 1、 Lachaise, Fabienne,Lafont, Rene. "ECDYSTEROID METABOLISM IN A CRAB: CARCINUS MAENAS L.". . p. 243 - 260. Retrieved 2007/10/02.