Drotaverine

Base Information Edit

Chemical Name:Drotaverine
CAS No.:14009-24-6
Molecular Formula:C24H31NO4
Molecular Weight:433.975
Hs Code.:2933990090
European Community (EC) Number:604-171-8,619-357-4
UNII:98QS4N58TW
DSSTox Substance ID:DTXSID60161227
Nikkaji Number:J9.603B
Wikipedia:Drotaverine
Wikidata:Q831929
NCI Thesaurus Code:C65489
Metabolomics Workbench ID:43699
ChEMBL ID:CHEMBL551978
Mol file:14009-24-6.mol

Synonyms:dihydroisoperparine;drotaverin;drotaverin hydrochloride;drotaverine;isodihydroperparine;No-shpa;No-spa;Nospan;Nospanum

Suppliers and Price of Drotaverine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Aronis compounds
1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline
1g
$ 145.00

American Custom Chemicals Corporation
1-(3,4-DIETHOXY-BENZYLIDENE)-6,7-DIETHOXY-1,2,3,4-TETRAHYDRO-ISOQUINOLINE 95.00%
5MG
$ 499.36

American Custom Chemicals Corporation
DROTAVERINE 95.00%
1G
$ 214.20

Total 67 raw suppliers

Chemical Property of Drotaverine Edit

Chemical Property:

Appearance/Colour:Pale yellow powder
Vapor Pressure:9.61E-13mmHg at 25°C
Melting Point:184 -188ºC
Refractive Index:1.6000 (estimate)
Boiling Point:564 °C at 760 mmHg
PKA:6.17±0.20(Predicted)
Flash Point:240.7 °C
PSA：48.95000
Density:1.097 g/cm³
LogP:5.25400
Water Solubility.:13.75g/L(37 oC)
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:397.22530847
Heavy Atom Count:29
Complexity:511

Purity/Quality:

99% ^*data from raw suppliers

1-(3,4-diethoxybenzylidene)-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC1=C(C=C(C=C1)C=C2C3=CC(=C(C=C3CCN2)OCC)OCC)OCC
Isomeric SMILES:CCOC1=C(C=C(C=C1)/C=C\2/C3=CC(=C(C=C3CCN2)OCC)OCC)OCC
Recent ClinicalTrials:Drotaverine in Dysmenorrhoea Treatment

Technology Process of Drotaverine

There total 2 articles about Drotaverine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: