Bitertanol

Base Information Edit

Chemical Name:Bitertanol
CAS No.:55179-31-2
Molecular Formula:C20H23N3O2
Molecular Weight:337.422
Hs Code.:2933990015
European Community (EC) Number:259-513-5
DSSTox Substance ID:DTXSID2037502
Nikkaji Number:J11.455C
Wikidata:Q1821798
Metabolomics Workbench ID:67986
ChEMBL ID:CHEMBL1566634
Mol file:55179-31-2.mol

Synonyms:1-(4-biphenylyloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol;bitertanol

Suppliers and Price of Bitertanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Bitertanol mixture of diastereo isomers
250mg
$ 32.20

Medical Isotopes, Inc.
Bitertanol
1 g
$ 1460.00

DC Chemicals
Bitertanol >98%
250 mg
$ 300.00

Cayman Chemical
Bitertanol ≥98%
50mg
$ 81.00

Cayman Chemical
Bitertanol ≥98%
25mg
$ 43.00

American Custom Chemicals Corporation
BITERTANOL 95.00%
1G
$ 1360.00

American Custom Chemicals Corporation
BITERTANOL 95.00%
100MG
$ 520.00

Total 74 raw suppliers

Chemical Property of Bitertanol Edit

Chemical Property:

Appearance/Colour:clear browm clear liquid
Vapor Pressure:1.49E-12mmHg at 25°C
Melting Point:49-50°C
Refractive Index:1.586
Boiling Point:541.4 °C at 760 mmHg
PKA:13.40±0.20(Predicted)
Flash Point:281.2 °C
PSA：60.17000
Density:1.14 g/cm³
LogP:3.92970
Water Solubility.:A 2.7 mg l-1 (20 °C) B 1.1 mg l-1 (20 °C)
XLogP3:4.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:337.17902698
Heavy Atom Count:25
Complexity:398

Purity/Quality:

99% ^*data from raw suppliers

Bitertanol mixture of diastereo isomers ^*data from reagent suppliers

Safty Information:

Pictogram(s): T
Hazard Codes:T
Statements: 22-23
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Pesticides -> Fungicides
Canonical SMILES:CC(C)(C)C(C(N1C=NC=N1)OC2=CC=C(C=C2)C3=CC=CC=C3)O
Description Bitertanol is a broad-spectrum triazole fungicide that is active against a variety of fungi, including V. inaequalis and V. pirina, which are responsible for apple and pear scab, respectively, as well as S. mors-uvae and P. ribis, which are responsible for American gooseberry mildew and leaf spot in black currants, respectively. It is active against isolates of V. inaequalis (MICs = 0.6 and 1 μg/ml) but repeated use leads to resistance and cross-resistance (MICs = 9.8-13 μg/ml for bitertanol-resistant isolates). Bitertanol inhibits the cytochrome P450 (CYP450) isoform CYP3A4 (IC50 = 2.74 μM) and inhibits androgenic activity induced by the androgen receptor agonist DHT in a yeast two-hybrid assay (IC50 = 79.85 μM). In rats, bitertanol (10-300 mg/kg, i.p.) increases operant responding on one- and five-minute fixed interval schedules with no effect on motor activity.
Uses Agricultural fungicide. Bitertanol is a foliar-applied triazole fungicide used to protect tropical and subtropical crops in agriculture, in particular bananas. Bitertanol has effects on behavior that are similar to those of psychomotor stimulants. Bitertanol is used as a seed treatment on winter wheat and barley and as a foliar treatment to control diseases on bananas, ornamentals, fruit and vegetables.

Technology Process of Bitertanol

There total 3 articles about Bitertanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: