Leonuriside A

Base Information

• Chemical Name: Leonuriside A
• CAS No.: 121748-12-7
• Molecular Formula: C14H20 O9
• Molecular Weight: 332.307
• Wikidata: Q105182715
• Mol file: 121748-12-7.mol

Synonyms:Leonuriside A;CHEBI:169679;4-Hydroxy-2,6-dimethoxyphenyl glucoside;2,6-Dimethoxy-p-hydroquinone 1-O-beta-glucopyranoside;2-(4-HYDROXY-2,6-DIMETHOXYPHENOXY)-6-(HYDROXYMETHYL)OXANE-3,4,5-TRIOL

Chemical Property of Leonuriside A

Chemical Property:

• Melting Point: 232-234 °C
• Boiling Point: 603.7±55.0 °C(Predicted)
• PSA: 138.07000
• Density: 1.490±0.06 g/cm3(Predicted)
• LogP: -1.41190
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 5
• Exact Mass: 332.11073221
• Heavy Atom Count: 23
• Complexity: 354

Purity/Quality:

LeonurisideA ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC2C(C(C(C(O2)CO)O)O)O)OC)O
• Uses: Leonuriside A is a bioactive glycoside found in the twigs of Litsea cubeba, and is an α-amylase inhibitor.

Technology Process of Leonuriside A

There total 1 articles about Leonuriside A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C29H40O13 → 1,4-dihydroxy-2,6-dimethoxybenzene 1-O-β-D-glucopyranoside (121748-12-7) + (1′R,3′S,5′R,8′S,2Z,4E)-dihydrophaseic acid

Guidance literature:

With water; lithium hydroxide; In methanol; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1016/j.phytochem.2019.03.021

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 1,4-dihydroxy-2,6-dimethoxybenzene 1-O-β-D-glucopyranoside (121748-12-7) → 1-(O-2,4,6-trimethoxyphenyl)-β-D-glucopyranoside (125288-25-7)

Guidance literature:

In methanol; at 0 ℃; for 1h;

DOI:10.1016/S0031-9422(00)98001-4

Downstream raw materials:

1-(O-2,4,6-trimethoxyphenyl)-β-D-glucopyranoside

Refernces