Bis(4-amino-3-methylcyclohexyl)methane

Base Information

• Chemical Name: Bis(4-amino-3-methylcyclohexyl)methane
• CAS No.: 6864-37-5
• Deprecated CAS: 116397-45-6,167678-63-9,32911-59-4,39283-21-1,60120-40-3,74926-18-4,300690-18-0,635305-12-3,1204529-54-3,1451256-40-8,1493800-15-9,1437984-69-4,167678-63-9,300690-18-0,32911-59-4,39283-21-1,60120-40-3,74926-18-4
• Molecular Formula: C15H30 N2
• Molecular Weight: 238.417
• Hs Code.: 29213000
• European Community (EC) Number: 229-962-1
• ICSC Number: 1464
• UNII: 3K4H01E55X
• DSSTox Substance ID: DTXSID6029670
• Nikkaji Number: J39.615J
• ChEMBL ID: CHEMBL3189048
• Mol file: 6864-37-5.mol

Synonyms:bis(4-amino-3-methylcyclohexyl)methane;laromin C

Chemical Property of Bis(4-amino-3-methylcyclohexyl)methane

Chemical Property:

• Appearance/Colour: COLOURLESS TO YELLOW LIQUID
• Vapor Pressure: 0.08Pa at 20℃
• Melting Point: -7°C
• Refractive Index: n20/D 1.499(lit.)
• Boiling Point: 289.6 °C at 760 mmHg
• PKA: 11.03±0.70(Predicted)
• Flash Point: >230 °F
• PSA: 52.04000
• Density: 0.94 g/mL at 25 °C(lit.)
• LogP: 4.30410
• Storage Temp.: Store below +30°C.
• Solubility.: 3.6g/l
• Water Solubility.: 2.01g/L at 20℃
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 238.240898965
• Heavy Atom Count: 17
• Complexity: 217

Purity/Quality:

99.9% ^*data from raw suppliers

4,4''-Methylenebis(2-methylcyclohexanamine) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Moderately toxic by inhalation.
• Hazard Codes: T,C,N
• Statements: 22-23/24-35-51/53
• Safety Statements: 26-36/37/39-45-61

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC1CC(CCC1N)CC2CCC(C(C2)C)N
• Inhalation Risk: A harmful contamination of the air will not or will only very slowly be reached on evaporation of this substance at 20 °C; on spraying or dispersing, however, much faster.
• Effects of Short Term Exposure: The substance is very corrosive to the eyes and skin. The substance is corrosive to the respiratory tract. Corrosive on ingestion. Inhalation of high levels of the aerosol may cause lung oedema.
• Effects of Long Term Exposure: The substance may have effects on the skin. This may result in chronic disease (scleroderma). The substance may have effects on the blood, cardiovascular system, kidneys and liver. This may result in anaemia, cardiac disorders, kidney impairment and liver impairment.
• Uses: 4,4′-Methylenebis(2-methylcyclohexylamine) (MMCA) may be used:in the synthesis of fully aliphatic polyimidesin the synthesis of fully aliphatic polyimide-siloxanes (APISiO)to prepare epoxy resin with trimethylolpropane triglycidyl ether, used for the characterization of the structural organization in dragline silk by transmission X-ray microscopy (STXM). 4,4'-Methylenebis(2-methylcyclohexylamine) can be used as epoxy curing agents.

Technology Process of Bis(4-amino-3-methylcyclohexyl)methane

There total 3 articles about Bis(4-amino-3-methylcyclohexyl)methane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.4%

3,3'-dimethyl-4,4'-diaminodiphenylmethane (838-88-0) → bis-(4-amino-3-methylcyclohexyl)-methane (6864-37-5)

Guidance literature:

With ruthenium on aluminium oxide; ammonium aluminium sulfate; hydrogen; In tetrahydrofuran; at 160 ℃; for 4h; under 60006 Torr; Acidic conditions; Large scale;

Reference yield:

3,3'-dimethyl-4,4'-diaminodiphenylmethane (838-88-0) → (4-amino-3-methylcyclohexyl)(4-amino-3-methylphenyl)methane (1201895-82-0) + bis-(4-amino-3-methylcyclohexyl)-methane (6864-37-5)

Guidance literature:

With hydrogen; silica gel; at 230 ℃; for 9h; under 75007.5 - 202520 Torr; Product distribution / selectivity; Autoclave; Inert atmosphere;

Reference yield:

→ bis-(4-amino-3-methylcyclohexyl)-methane (6864-37-5)

Guidance literature:

3,3'-Dimethyl-4,4'-Diaminodiphenylmethan , CoO-H2/Druck;

upstream raw materials:

3,3'-dimethyl-4,4'-diaminodiphenylmethane

Downstream raw materials:

C₃₁H₅₄N₂O₈

C₁₅H₁₉ClN₂O

C₁₆H₂₁ClN₂O

C₁₇H₁₈ClN₃O

Refernces

• 1、 -. "Catalyst and process for hydrogenating aromatics". Page/Page column 21; 22. . Retrieved 2015/07/27.
• 2、 -. "CONTINUOUS METHOD AND REACTOR FOR HYDROGENATING ORGANIC COMPOUNDS". Page/Page column 9. . Retrieved 2011/06/24.