N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

Base Information

• Chemical Name: N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
• CAS No.: 102-60-3
• Deprecated CAS: 118549-63-6,61702-85-0,139352-19-5,70992-50-6,1087406-22-1,139352-19-5,61702-85-0,70992-50-6
• Molecular Formula: C₁₄H₃₂N₂O₄
• Molecular Weight: 292.419
• Hs Code.: 29221980
• European Community (EC) Number: 203-041-4
• NSC Number: 760394,369219
• UNII: Q4R969U9FR
• DSSTox Substance ID: DTXSID9026689
• Nikkaji Number: J5.514J
• Wikidata: Q26841009
• NCI Thesaurus Code: C76706
• RXCUI: 1314349
• ChEMBL ID: CHEMBL1573178
• Mol file: 102-60-3.mol

Synonyms:1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol;1,1',1'',1'''-(ethylenedinitrilo)tetra-2-propanol monotosylate;N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine;Quadrol;tetrahydroxypropyl ethylenediamine

Chemical Property of N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

Chemical Property:

• Appearance/Colour: clear colorless to pale yellow viscous liquid
• Vapor Pressure: 1 mm Hg ( 20 °C)
• Melting Point: 32 °C
• Refractive Index: n20/D 1.4812(lit.)
• Boiling Point: 369.1 °C at 760 mmHg
• PKA: 14.23±0.20(Predicted)
• Flash Point: 145.7 °C
• PSA: 87.40000
• Density: 1.1 g/cm³
• LogP: -0.88640
• Storage Temp.: Store below +30°C.
• Water Solubility.: miscible
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 11
• Exact Mass: 292.23620751
• Heavy Atom Count: 20
• Complexity: 199

Purity/Quality:

99% ^*data from raw suppliers

Quadrol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 43-36
• Safety Statements: 36/37-37-24-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: CC(CN(CCN(CC(C)O)CC(C)O)CC(C)O)O
• Uses: sweetener N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be used as cross-linking agent and catalyst in the manufacture of urethan foams; in epoxy resin curing; as complexing agent, humectant, emulsifier, plasticizer. N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine is used as a solvent and preservative. A component of the bacteria-killing substance in sugarcane, it is very alkaline and may be irritating to the skin and mucous membranes. It might also cause skin sensitization.

Technology Process of N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

There total 4 articles about N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethylenediamine (107-15-3,85404-18-8) + methyloxirane (75-56-9,16033-71-9) → N,N,N',N'-tetra(2-hydroxypropyl)ethylenediamine (102-60-3,121651-65-8,121651-66-9,121651-67-0,121651-68-1)

Guidance literature:

at 25 ℃; for 240h; Inert atmosphere;

DOI:10.1016/j.molliq.2020.112579

Reference yield:

ethylenediamine (107-15-3,85404-18-8) + methyloxirane (75-56-9,16033-71-9) → N-(2-hydroxypropyl)ethylenediamine (123-84-2) + N,N′-bis(2-hydroxypropyl)ethylenediamine (3270-73-3) + N,N,N',N'-tetra(2-hydroxypropyl)ethylenediamine (102-60-3,121651-65-8,121651-66-9,121651-67-0,121651-68-1) + N,N,N'-tri(2-hydroxypropyl)ethylenediamine (10507-78-5)

Guidance literature:

at 99.9 ℃; under 760 Torr;

Reference yield:

N,N,N'-tri(2-hydroxypropyl)ethylenediamine (10507-78-5) + methyloxirane (75-56-9,16033-71-9) → N-(2-hydroxypropyl)ethylenediamine (123-84-2) + N,N′-bis(2-hydroxypropyl)ethylenediamine (3270-73-3) + N,N,N',N'-tetra(2-hydroxypropyl)ethylenediamine (102-60-3,121651-65-8,121651-66-9,121651-67-0,121651-68-1)

Guidance literature:

at 69.9 - 89.9 ℃; under 760 Torr; Rate constant; Kinetics; Thermodynamic data; ΔE(excit.), var. temps.;

upstream raw materials:

ethylenediamine

methyloxirane

N,N,N'-tri(2-hydroxypropyl)ethylenediamine

Downstream raw materials:

4,8,4',8'-tetramethyl-2,2'-diphenyl-6,6'-ethane-1,2-diyl-bis-[1,3,6,2]dioxazaborocane

Refernces

• 1、 Plucinski, Janusz,Prystasz, Henryka. "KINETICS AND REACTION MECHANISM OF PROPYLENE OXIDE WITH ETHYLENEDIAMINE". . p. 2201 - 2208. Retrieved 2007/10/02.