Fluorene-2-carboxaldehyde

Base Information

• Chemical Name: Fluorene-2-carboxaldehyde
• CAS No.: 30084-90-3
• Deprecated CAS: 93621-79-5
• Molecular Formula: C14H10O
• Molecular Weight: 194.233
• Hs Code.: 29122990
• European Community (EC) Number: 250-035-2
• UNII: 1QDR3MEU7Z
• DSSTox Substance ID: DTXSID10184168
• Nikkaji Number: J69.712E
• Wikidata: Q83055048
• ChEMBL ID: CHEMBL4474679
• Mol file: 30084-90-3.mol

Synonyms:9H-fluorene-2-carboxaldehyde

Chemical Property of Fluorene-2-carboxaldehyde

Chemical Property:

• Appearance/Colour: Sallow powder
• Vapor Pressure: 1.39E-05mmHg at 25°C
• Melting Point: 83-85 °C(lit.)
• Refractive Index: 1.681
• Boiling Point: 367.1 °C at 760 mmHg
• Flash Point: 232.5 °C
• PSA: 17.07000
• Density: 1.213 g/cm³
• LogP: 3.07030
• Storage Temp.: Store below +30°C.
• Sensitive.: Air & Light Sensitive
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 194.073164938
• Heavy Atom Count: 15
• Complexity: 248

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fluorene-2-carboxaldehyde ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Polycyclic Aromatic Hydrocarbons
• Canonical SMILES: C1C2=CC=CC=C2C3=C1C=C(C=C3)C=O
• Uses: Fluorene-2-carboxaldehyde was used in the preparation of 2-hydroxyl-methyl-fluorene.

Technology Process of Fluorene-2-carboxaldehyde

There total 10 articles about Fluorene-2-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

9H-fluorene (86-73-7) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 9H-fluorene-2-carbaldehyde (30084-90-3)

Guidance literature:

With silica gel; trichlorophosphate; for 0.0333333h; Microwave irradiation (300 W);

Reference yield:

9H-fluorene (86-73-7) + chloromethylene-formamidine (4483-79-8) → 9H-fluorene-2-carbaldehyde (30084-90-3)

Guidance literature:

With aluminium trichloride; 1,1,2,2-tetrachloroethane; at 50 ℃; Eintragen des Reaktionsgemisches in ein Gemisch von Eis und wss. HCl und anschliessendes Erhitzen auf Siedetemperatur;

DOI:10.1039/jr9360000339

Reference yield:

N-methyl-N-phenyl-9H-fluorene-2-carboxamide → 9H-fluorene-2-carbaldehyde (30084-90-3)

Guidance literature:

With tetrahydrofuran; lithium aluminium tetrahydride;

upstream raw materials:

9H-fluorene

chloromethylene-formamidine

chloroform

hexamethylenetetramine

Downstream raw materials:

2-methyl-9H-fluorene

[1-(9H-Fluoren-2-yl)-meth-(E)-ylidene]-(4-tetradecyloxy-phenyl)-amine

[1-(9H-Fluoren-2-yl)-meth-(E)-ylidene]-(4-propoxy-phenyl)-amine

[1-(9H-Fluoren-2-yl)-meth-(E)-ylidene]-(4-pentyloxy-phenyl)-amine

Refernces

• 1、 -. "Process for nucleophilic fluoroalkylation of aldehydes". . . Retrieved 2008/06/13.