3,4-Dibromosulfolane

Base Information

• Chemical Name: 3,4-Dibromosulfolane
• CAS No.: 15091-30-2
• Molecular Formula: C4H6 Br2 O2 S
• Molecular Weight: 277.964
• Hs Code.: 2934999090
• European Community (EC) Number: 804-276-0
• NSC Number: 75382,39636
• DSSTox Substance ID: DTXSID80884784
• Nikkaji Number: J48.871B
• Mol file: 15091-30-2.mol

Synonyms:3,4-Dibromosulfolane;15091-30-2;3,4-Dibromotetrahydrothiophene 1,1-dioxide;3,4-dibromothiolane 1,1-dioxide;Thiophene, 3,4-dibromotetrahydro-, 1,1-dioxide;C4H6Br2O2S;3,4-Dibromotetrahydrothiophene-1,1-dioxide;MFCD00022536;NSC 39636;Thiophene, tetrahydro-3,4-dibromo-, 1,1-dioxide;BRN 0119352;3,4-Dibromotetrahydrothiophene1,1-dioxide;Thiophene, 3,4-dibromotetrahydro-, 1,1-dioxide, (3R,4R)-rel-;Thiophene,4-dibromo-, 1,1-dioxide;Thiophene,4-dibromotetrahydro-, 1,1-dioxide;7311-84-4;NSC39636;NCIOpen2_004531;3,4-DIBROMO SULFOLANE;SCHEMBL2681109;C4-H6-Br2-O2-S;DTXSID80884784;NSC75382;BBL012241;NSC-39636;NSC-75382;STK803097;AKOS003244555;AKOS016039456;BS-9949;3,4-dibromo-1lambda6-thiolane-1,1-dione;LS-153183;CS-0106384;D0679;FT-0637178;EN300-86107;Thiophene,3,4-dibromotetrahydro-,1,1-dioxide;F12433;A809086;TRANS-3,4-DIBROMOTETRAHYDROTHIOPHENE 1,1 -DIOXIDE, 97%

Chemical Property of 3,4-Dibromosulfolane

Chemical Property:

• Melting Point: 143 °C
• Boiling Point: 402.3°Cat760mmHg
• Flash Point: 197.1°C
• PSA: 42.52000
• Density: 2.241g/cm³
• LogP: 2.02260
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 277.84348
• Heavy Atom Count: 9
• Complexity: 177

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4-Dibromosulfolane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(C(CS1(=O)=O)Br)Br

Technology Process of 3,4-Dibromosulfolane

There total 6 articles about 3,4-Dibromosulfolane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

3-Sulfolene (77-79-2) → 3,4-dibromosulfolane (7311-84-4,15091-30-2,125392-77-0)

Guidance literature:

With bromine; In chloroform;

Reference yield:

3-Sulfolene (77-79-2) → 3,4-dibromo-2,3,4,5-tetrahydrothiophene-1,1-dioxide (15091-30-2)

Guidance literature:

With N-Bromosuccinimide; In methanol; at 20 - 30 ℃;

DOI:10.1055/s-0037-1611277

Reference yield:

3-Sulfolene (77-79-2) → trans-3,4-dibromosulfolane (7311-84-4,15091-30-2,125392-77-0)

Guidance literature:

With chloroform; bromine;

DOI:10.1021/ja01636a060

upstream raw materials:

3,4-dibromo-tetrahydro-thiophene

3-Sulfolene

Downstream raw materials:

(1,1-Dioxo-2,3-dihydro-1H-1λ⁶-thiophen-3-yl)-(2-iodo-phenyl)-amine

3,4-diaminotetrahydrothiophene 1,1-dioxide dihydrochloride

4-benzylamino-2-thiolene 1,1-dioxide

2-amino-5a,6,8,8a-tetrahydro-4H-7λ⁶-thieno[3',4':4,5][1,3]thiazolo[3,2-a]pyrimidin-4-one 7,7-dioxide

Refernces

• 1、 Sokolov, Andriy,Golovach, Sergey,Kozlinsky, Ihor,Dolia, Krystyna,Tolmachev, Andrey A.,Kuchkovska, Yuliya,Grygorenko, Oleksandr O.. "Diastereoselective Synthesis of Cyclic sp 3 -Enriched cis -β-Alkoxysulfonyl Chlorides". supporting information. p. 848 - 858. Retrieved 2019/02/10.
• 2、 -. "1,3-dibenzyl-4-halohexahydro-1H-thieno[3,4-d]imidazol-2(3H)-one intermediates". . . Retrieved 2008/06/13.