9-ETHYNYL-9-FLUORENOL

Base Information

• Chemical Name: 9-ETHYNYL-9-FLUORENOL
• CAS No.: 13461-74-0
• Molecular Formula: C15H10 O
• Molecular Weight: 206.244
• Hs Code.: 29062900
• Mol file: 13461-74-0.mol

Synonyms:Fluoren-9-ol,9-ethynyl- (6CI,7CI,8CI); 9-Ethynyl-9-hydroxyfluorene;9-Ethynyl-9H-fluoren-9-ol; 9-Ethynylfluoren-9-ol; 9-Hydroxy-9-ethynylfluorene

Chemical Property of 9-ETHYNYL-9-FLUORENOL

Chemical Property:

• Vapor Pressure: 2.69E-06mmHg at 25°C
• Melting Point: 107-110 °C
• Boiling Point: 375.2°Cat760mmHg
• PKA: 11.37±0.20(Predicted)
• Flash Point: 178.1°C
• PSA: 20.23000
• Density: 1.26g/cm³
• LogP: 2.53610

Purity/Quality:

98%,99%, ^*data from raw suppliers

9-Ethynyl-9-fluorenol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38-41
• Safety Statements: 37/39-26-39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 9-ETHYNYL-9-FLUORENOL

There total 12 articles about 9-ETHYNYL-9-FLUORENOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

9-(2-(trimethylsilyl)ethynyl)-9H-fluoren-9-ol (244767-23-5) → 9-ethynylfluoren-9-ol (13461-74-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.orglett.0c03717

Reference yield: 79.0%

9H-fluorene (86-73-7) + ethylene dibromide (106-93-4) → 9-ethynylfluoren-9-ol (13461-74-0)

Guidance literature:

With sodium hydroxide; cetyltrimethylammonim bromide; In water; dimethyl sulfoxide; at 20 ℃; for 10h;

DOI:10.1016/j.tet.2007.08.029

Reference yield: 73.0%

9-fluorenone (486-25-9,952573-42-1) + ethynylmagnesium chloride (65032-27-1) → 9-ethynylfluoren-9-ol (13461-74-0)

Guidance literature:

9-fluorenone; ethynylmagnesium chloride; In tetrahydrofuran; for 12h; Reflux;

With ammonium chloride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tet.2010.11.092

upstream raw materials:

9-fluorenone

sodium acetylide

acetylene

lithium acetylide-ethylenediamine complex

Downstream raw materials:

9-<2.3.4.5-Tetraphenyl-phenyl>-fluorenol-(9)

9-phenylethynylfluoren-9-ol

fac-[RuCl₃(CC(H)=C₁₃H₈)(1,1'-bis(diphenylphosphino)ferrocene)]

fac-[RuBr₃(CC(H)=C₁₃H₈)(1,1'-bis(diphenylphosphino)ferrocene)]

Refernces

• 1、 Lavie,Bergmann. "-". . p. 367,373. Retrieved 1953.
• 2、 Bovonsombat, Pakorn,Mc Nelis, Edward. "A new approach to the functionalization of phenanthrenequinone". . p. 6431 - 6432. Retrieved 1994.
• 3、 Lázaro-Milla, Carlos,Macicior, Jon,Yanai, Hikaru,Almendros, Pedro. "Trifluorosulfonylation Cascade in Allenols: Stereocontrolled Synthesis of Bis(triflyl)enones". supporting information. p. 8983 - 8989. Retrieved 2020/07/09.