(3,4-Dichlorophenyl)hydrazine;hydron;chloride

Base Information

• Chemical Name: (3,4-Dichlorophenyl)hydrazine;hydron;chloride
• CAS No.: 19763-90-7
• Molecular Formula: C6H6Cl2N2^.HCl
• Molecular Weight: 213.494
• Hs Code.: 29280000
• Mol file: 19763-90-7.mol

Synonyms:AKOS015890165

Chemical Property of (3,4-Dichlorophenyl)hydrazine;hydron;chloride

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 0.00236mmHg at 25°C
• Melting Point: 230 °C (dec.)(lit.)
• Boiling Point: 288.3 °C at 760 mmHg
• Flash Point: 128.2 °C
• PSA: 38.05000
• Density: 1.475 g/cm³
• LogP: 3.85430
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 211.967481
• Heavy Atom Count: 11
• Complexity: 110

Purity/Quality:

99% ^*data from raw suppliers

3,4-Dichlorophenylhydrazine Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-37/39-36/37/39-22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: [H+].C1=CC(=C(C=C1NN)Cl)Cl.[Cl-]
• Uses: 3,4-Dichlorophenylhydrazine hydrochloride was used to prepare ethyl 2-(3,4-dichlorophenyl)hydrazinecarboxylate.

Technology Process of (3,4-Dichlorophenyl)hydrazine;hydron;chloride

There total 1 articles about (3,4-Dichlorophenyl)hydrazine;hydron;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

m,p-dichloroaniline (95-76-1) → 3,4-dichlorophenylhydrazine hydrochloride (19763-90-7)

Guidance literature:

m,p-dichloroaniline; With hydrogenchloride; sodium nitrite; In tetrahydrofuran; at 5 ℃; for 0.5h;

With sodium hydrogensulfite; In tetrahydrofuran; at 70 ℃; for 0.3h;

With hydrogenchloride; In tetrahydrofuran; for 1h; Solvent; Reagent/catalyst; Temperature;

Reference yield: 99.0%

3,4-dichlorophenylhydrazine hydrochloride (19763-90-7) + ethyl 2,4-diketopentanoate (615-79-2) → ethyl 1-(3,4-dichlorophenyl)-5-methyl-1H-pyrazole-3-carboxylate (1020724-07-5)

Guidance literature:

With acetic acid; for 1h; Reflux;

Reference yield: 92.6%

2,3-Dimethylmaleic anhydride (766-39-2) + 3,4-dichlorophenylhydrazine hydrochloride (19763-90-7) → 2-(3,4-dichlorophenyl)-6-hydroxy-4,5-dimethylpyridazin-3(2H)-one

Guidance literature:

With hydrogenchloride; In water; for 6h; Reflux;

upstream raw materials:

m,p-dichloroaniline

Downstream raw materials:

3,5-Dimethyl-benzoic acid N'-(3,4-dichloro-phenyl)-hydrazide

2-(3,4-dichloro-phenyl)-5-methyl-2H-pyrazol-3-ylamine

2,3-Bis-[(3,4-dichloro-phenyl)-hydrazono]-propan-1-ol

N-(3,4-Dichloro-phenyl)-N'-[2,2,2-trifluoro-1-phenyl-eth-(Z)-ylidene]-hydrazine

Refernces

• 1、 Bi, Fangchao,Song, Di,Qin, Yinhui,Liu, Xingbang,Teng, Yuetai,Zhang, Na,Zhang, Panpan,Zhang, Nan,Ma, Shutao. "Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains". . p. 3179 - 3193. Retrieved 2019/06/17.
• 2、 Hofmann, Josefa,Jasch, Hannelore,Heinrich, Markus R.. "Oxidative radical arylation of anilines with arylhydrazines and dioxygen from air". . p. 2314 - 2320. Retrieved 2014/04/03.