Ginsenoside Rs3

Base Information

• Chemical Name: Ginsenoside Rs3
• CAS No.: 194861-70-6
• Molecular Formula: C44H74O14
• Molecular Weight: 827.05
• Mol file: 194861-70-6.mol

Synonyms:β-D-Glucopyranoside, (3β,12β)-12,20-dihydroxydammar-24-en-3-yl 2-O-(6-O-acetyl-β-D-glucopyranosyl)-;20S-6''-O-Acetylginsenoside Rg3;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl 2-O-(6-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside;

Chemical Property of Ginsenoside Rs3

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 154-157 °C
• Boiling Point: 891.6°Cat760mmHg
• PKA: 12.84±0.70(Predicted)
• Flash Point: 255.5°C
• PSA: 225.06000
• Density: 1.29g/cm³
• LogP: 2.71980

Purity/Quality:

Analysis control,HPLC≥95% ^*data from raw suppliers

GinsenosideRs3 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Ginsenoside Rs3

There total 4 articles about Ginsenoside Rs3 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

vinyl acetate (108-05-4,9003-20-7) + 20(R)-ginsenoside Rg3 (38243-03-7) → 20(R)-6''-O-acetylginsenoside Rg3 (194861-70-6)

Guidance literature:

With novozyme 435; In tetrahydrofuran; N,N-dimethyl-formamide; at 37 ℃; for 72h;

DOI:10.1002/hlca.200490165

Reference yield: 59.0%

vinyl acetate (108-05-4,9003-20-7) + ginsenoside Rg3 (14197-60-5,38243-03-7,126252-51-5) → ginsenoside Rs3 (194861-70-6)

Guidance literature:

With novozyme 435; In tert-Amyl alcohol; at 37 ℃; for 72h;

DOI:10.1002/hlca.200490165

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + (3β,12β,20R/20S)-12,20-dihydroxydammar-24-en-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside (126252-51-5) → (3β,12β,20R/20S)-12,20-dihydroxydammar-24-en-3-yl 2-O-(6-O-acetyl-β-D-glucopyranosyl)-β-D-glucopyranoside (194861-70-6)

Guidance literature:

With Novozym(R) 435; In tetrahydrofuran; N,N-dimethyl-formamide; at 45 ℃; for 72h;

DOI:10.1002/1522-2675(200207)85:7<1943::AID-HLCA1943>3.0.CO;2-T

upstream raw materials:

vinyl acetate

(3β,12β,20R/20S)-12,20-dihydroxydammar-24-en-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside

Ginsenoside Rb₁

20(R)-ginsenoside Rg₃

Refernces

• 1、 Gebhardt, Steffen,Bihler, Stefan,Schubert-Zsilavecz, Manfred,Riva, Sergio,Monti, Daniela,Falcone, Laura,Danieli, Bruno. "Biocatalytic generation of molecular diversity: Modification of ginsenoside Rb1 by β-1,4-Galactosyltransferase and Candida antarctica lipase". . p. 1943 - 1959. Retrieved 2002.