2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol

Base Information

• Chemical Name: 2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol
• CAS No.: 36366-93-5
• Molecular Formula: C14H22 O5
• Molecular Weight: 270.326
• Hs Code.: 2909499000
• European Community (EC) Number: 253-002-0
• UNII: Y050HYR4XA
• DSSTox Substance ID: DTXSID3041295
• Nikkaji Number: J332.279C
• Wikidata: Q27294091
• RXCUI: 1655970
• Mol file: 36366-93-5.mol

Synonyms:36366-93-5;2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol;Dowanol T 4Ph;2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]ethanol;Tetraethylene glycol monophenyl ether;BRN 3333301;EINECS 253-002-0;UNII-Y050HYR4XA;Y050HYR4XA;ETHANOL, 2-(2-(2-(2-PHENOXYETHOXY)ETHOXY)ETHOXY)-;Ethanol,2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]-;Ethanol, 2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]-;REWOPAL MPG 40;SCHEMBL224480;DTXSID3041295;11-Phenoxy-3,6,9-trioxaundecane-1-ol;LS-67010;Q27294091

Chemical Property of 2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol

Chemical Property:

• Vapor Pressure: 7.32E-07mmHg at 25°C
• Refractive Index: 1.4825 (estimate)
• Boiling Point: 392.4°Cat760mmHg
• Flash Point: 191.1°C
• PSA: 57.15000
• Density: 1.1g/cm³
• LogP: 1.10750
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 12
• Exact Mass: 270.14672380
• Heavy Atom Count: 19
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

2-[2-[2-(2-PHENOXYETHOXY)ETHOXY]ETHOXY]ETHANOL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)OCCOCCOCCOCCO

Technology Process of 2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol

There total 13 articles about 2-(2-(2-(2-Phenoxyethoxy)ethoxy)ethoxy)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-<2-<2-<2-(benzyloxy)ethoxy>ethoxy>ethoxy>ethoxybenzene (89346-83-8) → 2-<2-<2-(2-phenoxyethoxy)ethoxy>ethoxy>ethanol (36366-93-5,9004-78-8)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; for 12h; under 3102.9 Torr;

DOI:10.1021/jo00183a021

Reference yield: 72.0%

1-bromo-9-phenyl-3,6,9-trioxanonane (123824-57-7) + ethylene glycol (107-21-1) → 2-<2-<2-(2-phenoxyethoxy)ethoxy>ethoxy>ethanol (36366-93-5,9004-78-8)

Guidance literature:

With potassium hydroxide; In water; 1.) 115 deg C, 1h; 2.) 120 deg C, 1h;

DOI:10.1016/S0040-4020(01)85934-2

Reference yield: 62.0%

p-toluenesulfonic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester (77544-60-6) + phenol (108-95-2,27073-41-2) → 2-<2-<2-(2-phenoxyethoxy)ethoxy>ethoxy>ethanol (36366-93-5,9004-78-8)

Guidance literature:

DOI:10.1021/jo00303a024

upstream raw materials:

oxirane

phenol

2-<2-<2-<2-(benzyloxy)ethoxy>ethoxy>ethoxy>ethoxybenzene

1-bromo-9-phenyl-3,6,9-trioxanonane

Downstream raw materials:

2-<2-<2-<2-(nitrobenzoyloxy)ethoxy>ethoxy>ethoxy>ethoxybenzene

2-<2-<2-(2-benzoyloxyethoxy)ethoxy>ethoxy>ethoxybenzene

2-<2-<2-<2-(aminobenzoyloxy)ethoxy>ethoxy>ethoxy>ethoxybenzene

2-<2-<2-<2-<(diazonium tetrafluoroborate)benzoyloxy>ethoxy>ethoxy>ethoxy>ethoxybenzene

Refernces

• 1、 Kimura, Masaru,Kajita, Kazushige,Onoda, Naoyuki,Morosawa, Shiro. "The Development of a New Nitrating Agent: The Unusual Regioselective Nitration of Diphenylpolyethylene Glycols and Phenylpolyethylene Glycols with Trimethylsilyl Nitrate - BF3OEt2". . p. 4887 - 4892. Retrieved 2007/10/02.
• 2、 Loehr, Hans-Gerd,Voegtle, Fritz. "Chromoionophores, VII. Podands Carrying Terminal Electron-Donor- and -Acceptor Groups. Cation-Influenced Charge Transfer Absorption". . p. 914 - 921. Retrieved 2007/10/02.