Eleutheroside M

Base Information

• Chemical Name: Eleutheroside M
• CAS No.: 36284-77-2
• Molecular Formula: C₅₉H₉₆O₂₅
• Molecular Weight: 1205.4
• Wikidata: Q105186393
• Mol file: 36284-77-2.mol

Synonyms:Eleutheroside M;Hederacoside B;[6-[[3,4-Dihydroxy-6-(hydroxymethyl)-5-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxymethyl]-3,4,5-trihydroxyoxan-2-yl] 10-[4,5-dihydroxy-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate

Chemical Property of Eleutheroside M

Chemical Property:

• Melting Point: 223-226℃
• PSA: 392.59000
• Density: 1.46
• LogP: -1.51680
• XLogP3: -0.7
• Hydrogen Bond Donor Count: 14
• Hydrogen Bond Acceptor Count: 25
• Rotatable Bond Count: 13
• Exact Mass: 1204.62406854
• Heavy Atom Count: 84
• Complexity: 2350

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

Hederasaponin B ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OCC3C(C(C(C(O3)OC(=O)C45CCC(CC4C6=CCC7C8(CCC(C(C8CCC7(C6(CC5)C)C)(C)C)OC9C(C(C(CO9)O)O)OC1C(C(C(C(O1)C)O)O)O)C)(C)C)O)O)O)CO)O)O)O
• Uses: Hederasaponin B is an antiviral agent, extracted from Hedera helix, used in the treatment of hand, foot and mouth disease (HFMD). Steroidal saponin with potential antitumor activity.

Technology Process of Eleutheroside M

There total 2 articles about Eleutheroside M which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C88H122O37 → hederasaponin B (36284-77-2)

Guidance literature:

With sodium methylate; In methanol; at 20 ℃; for 5h;

DOI:10.1016/j.ejmech.2017.11.040

Reference yield:

ciwujianoside C4 (114906-75-1) → hederasaponin B (36284-77-2)

Guidance literature:

With potassium hydroxide; at 4 ℃; for 24h;

Reference yield:

hederasaponin B (36284-77-2) → β-hederin (75026-25-4,35790-95-5)

Guidance literature:

With potassium hydroxide; In water; at 110 ℃; for 2h;

DOI:10.1021/np990231n

upstream raw materials:

ciwujianoside C₄

Downstream raw materials:

β-hederin

methyl α-L-rhamnosyl-(1->4)-O-β-D-glucopyranosyl-(1->6)-(α and β)-D-glucopyranoside

Refernces

• 1、 Shao, Chun-Jie,Kasai, Ryoji,Xu, Jing-Da,Tanaka, Osamu. "Saponins from Leaves of Acanthopanax senticosus HARMS., Ciwujia; Structures of Ciwujianosides B, C1, C2, C3, C4, D1, D2 and E". . p. 601 - 608. Retrieved 2007/10/02.