METHANE (D1)

Base Information

• Chemical Name: METHANE (D1)
• CAS No.: 676-49-3
• Molecular Formula: CH3 D
• Molecular Weight: 17.0348
• Mol file: 676-49-3.mol

Synonyms:Deuteriomethane;Methane (CH3D); Monodeuteriomethane; Monodeuteromethane

Chemical Property of METHANE (D1)

Chemical Property:

• Appearance/Colour: colourless gas
• Vapor Pressure: 205000mmHg at 25°C
• Melting Point: −183 °C(lit.)
• Boiling Point: −161 °C(lit.)
• Flash Point: -188℃
• PSA: 0.00000
• LogP: 0.63610

Purity/Quality:

99% ^*data from raw suppliers

Methane-d1 98 atom % D ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F+
• Hazard Codes: F+
• Statements: 12
• Safety Statements: 16-38-33-9

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A major oxidative metabolite of Pentoxifylline. A potent inhibitor of phosphatidic acid generation (IC50=0.6uM). Protects mice from endotoxic shock and attenuates sepsis-induced acute lung injury in pig

Technology Process of METHANE (D1)

There total 130 articles about METHANE (D1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

{(CD3)3Ta(μ-OCMe2CH2PPh2)2PtMe2}n → methane (34557-54-5,27936-85-2) + Monodeuteromethan (676-49-3) + methane-d3 (676-80-2) + methane (558-20-3)

Guidance literature:

In not given; thermolysis; mass spectroscopy;

Reference yield: 14.0%

methane (34557-54-5,27936-85-2) → methane-d2 (676-55-1) + Monodeuteromethan (676-49-3) + methane-d3 (676-80-2) + methane (558-20-3)

Guidance literature:

With deuterium; silica gel; palladium; at 464.9 ℃; for 1.66667h; Product distribution; Rate constant; further catalysts: silica-supported palladium/silver alloy (percent Pd 0-75);

Reference yield:

ethanol-1,1-d2 (1859-09-2) → paraformaldehyde-d2 (1664-98-8,43094-80-0) + 1-deuterio-acetaldehyde (4122-13-8) + methane (34557-54-5,27936-85-2) + Monodeuteromethan (676-49-3) + ethylene-1,1-d2 (6755-54-0)

Guidance literature:

under 0.5 - 10 Torr; Product distribution; Mechanism; Irradiation; unlabelled alcohol, in the presence of iodine;

upstream raw materials:

methyl bromide

methyl magnesium iodide

methyl radical

methane

Downstream raw materials:

methane-d3

methane

Refernces

• 1、 Miyashita, Akira,Saida, Yoshiko. "Activation of Methane Promoted by NeohexylPt(II) Complexes. Isolation of MethylPt(II) Complexes". . p. 2263 - 2266. Retrieved 1994.
• 2、 Cameron, Charles J.,Felkin, Hugh,Fillebeen-Khan, Tauqir,Forrow, Nigel J.,Guittet, Eric. "Activation of C-H Bonds in Saturated Hydrocarbons. H-D Exchange between Methane and Benzene catalysed by a Soluble Iridium Polyhydride System". . p. 801 - 802. Retrieved 1986.
• 3、 Hatano, Masaharu,Otsuka, Kiyoshi. "The Oxidative Coupling of Methane on Lithium Nickelate(III)". . p. 199 - 206. Retrieved 1989.
• 4、 Brouard, Mark,Macpherson, Martyn T.,Pilling, Michael J.. "Experimental and RRKM Modeling Study of the CH3+H and CH3+D Reactions". . p. 4047 - 4059. Retrieved 1989.
• 5、 Sattler, Aaron,Paccagnini, Michele,Lanci, Michael P.,Miseo, Sabato,Kliewer, Chris E.. "Platinum catalyzed c-h activation and the effect of metal-support interactions". . p. 710 - 720. Retrieved 2020/01/02.
• 6、 Pitman, Catherine L.,Miller, Alexander J. M.. "Photochemical Production of Ethane from an Iridium Methyl Complex". supporting information. p. 1906 - 1914. Retrieved 2017/06/14.