2α,3β,19α-Trihydroxyolean-12-en-28-oic acid

Base Information

• Chemical Name: 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid
• CAS No.: 31298-06-3
• Molecular Formula: C₃₀H₄₈O₅
• Molecular Weight: 488.708
• Mol file: 31298-06-3.mol

Synonyms:Arjunicacid;Arjuntriterpenic acid;

Chemical Property of 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 275-276 °C
• Refractive Index: 1.58
• Boiling Point: 602.688 °C at 760 mmHg
• PKA: 4.43±0.70(Predicted)
• Flash Point: 332.32 °C
• PSA: 97.99000
• Density: 1.19 g/cm³
• LogP: 5.17520

Purity/Quality:

98%,99%, ^*data from raw suppliers

Arjunic acid analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Arjunic acid may be used as an analytical standard for the determination of the analyte inTerminalia arjuna by reversed-phase high-performance liquid chromatography with photodiode array detection and in medicinal plant extracts by liquid chromatography-atmospheric pressure photoionization tandem mass spectrometric (LC-APPI-MS/MS) method.

Technology Process of 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid

There total 5 articles about 2α,3β,19α-Trihydroxyolean-12-en-28-oic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

arjunoside IV → 6-deoxy-L-mannose (84985-25-1,478518-52-4) + (2α,3β,19α)-2,3,19-trihydroxyolean-12-en-28-oic acid (31298-06-3)

Guidance literature:

With sulfuric acid; In methanol; for 6h; Heating;

DOI:10.1016/0031-9422(82)83042-2

Reference yield:

arjunoside III → β-D-glucurono-6,3-lactone (18281-92-0) + (2α,3β,19α)-2,3,19-trihydroxyolean-12-en-28-oic acid (31298-06-3)

Guidance literature:

With sulfuric acid; In methanol; for 6h; Heating;

DOI:10.1016/0031-9422(82)83042-2

Reference yield:

2α,3β,19α-trihydroxy-oleanolic acid-28-O-β-D-glucopyranoside (31297-79-7) → (2α,3β,19α)-2,3,19-trihydroxyolean-12-en-28-oic acid (31298-06-3)

Guidance literature:

With sulfuric acid; In methanol;

upstream raw materials:

2α,3β,19α-trihydroxy-oleanolic acid-28-O-β-D-glucopyranoside

Downstream raw materials:

2,3-di-O-benzoylarjunic acid

2-O-p-anisoylarjunic acid

2,3-di-O-p-nitrobenzoylarjunic acid

Refernces

• 1、 Anjaneyulu, A. S. R.,Prasad, A. V. Rama. "CHEMICAL EXAMINATION OF THE ROOTS OF TERMINALIA ARJUNA - THE STRUCTURES OF ARJUNOSIDE III AND ARJUNOSIDE IV, TWO NEW TRITERPENOID GLYCOSIDES". . p. 2057 - 2060. Retrieved 2007/10/02.