Elcatonin

Base Information

• Chemical Name: Elcatonin
• CAS No.: 60731-46-6
• Molecular Formula: C148H244 N42 O47
• Molecular Weight: 3364.34
• Hs Code.: 2937190090
• NCI Thesaurus Code: C96281
• Mol file: 60731-46-6.mol

Synonyms:1,7-Asu-calcitonin;avicatonin;calcitonin, aminosuberine(1,7)-;calcitonin, Asu(1,7)-;calcitonin, eel, Asu(1,7)-;Carbicalcin;carbocalcitonin;Diatin;Elactonina Ur;elcatonin;Elcatonina CEPA;L-aminosuberylcalcitonin

Chemical Property of Elcatonin

Chemical Property:

• Appearance/Colour: White powder.
• PSA: 1435.94000
• Density: 1.49±0.1 g/cm3(Predicted)
• LogP: -1.15300
• Storage Temp.: -15°C
• XLogP3: -14.1
• Hydrogen Bond Donor Count: 48
• Hydrogen Bond Acceptor Count: 52
• Rotatable Bond Count: 97
• Exact Mass: 3362.8027579
• Heavy Atom Count: 237
• Complexity: 7890

Purity/Quality:

98% ^*data from raw suppliers

Elcatonin ^*data from reagent suppliers

Safty Information:

• Pictogram(s): A poison by ingestion.
• Hazard Codes: A poison by ingestion.

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC1C(=O)NC(C(=O)NC(C(=O)NC(CCCCCC(=O)OCC(C(=O)NC(C(=O)N1)CC(=O)N)N)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NCC(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)O)C(=O)NC(CC(C)C)C(=O)NC(CC2=CN=CN2)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)NC(C(C)O)C(=O)NC(CC3=CC=C(C=C3)O)C(=O)N4CCCC4C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)O)C(=O)NC(CC(=O)O)C(=O)NC(C(C)C)C(=O)NCC(=O)NC(C)C(=O)NCC(=O)NC(C(C)O)C(=O)N5CCCC5C(=O)N)C(C)O)CO
• Description: Elcatonin (molecular formula: C148H244N42O47) is a kind of single, non-glycosylated polypeptide chain consisting of 31 amino acids. It is a calcitonin derivative, and is used as an anti-parathyroid agent. It is mainly used for remitting and eliminating the pain induced by Osteoporosis. It has several physiological effects including: (1) inhibit the absorption and autolysis of bones, thus leading to the reduction of the blood calcium level; (2) inhibit the dissolving and transferring of bone salts, further promoting the excretion of calcium and phosphorus in urine; (3) it inhibits the process of calcium, phosphorus and sodium re-absorption by renal tubules.
• Uses: Osteoporosis; Hypercalcemia; Paget’s disease