Phenylcarbamic acid phenylmethyl ester

Base Information

• Chemical Name: Phenylcarbamic acid phenylmethyl ester
• CAS No.: 3422-02-4
• Molecular Formula: C14H13NO2
• Molecular Weight: 227.263
• Hs Code.: 2924299090
• Mol file: 3422-02-4.mol

Synonyms:Benzyl phenylcarbamate;Phenylcarbamic acid phenylmethyl ester;Benzyl N-phenylcarbamate;Carbamic acid,phenyl-,phenylmethyl ester;

Chemical Property of Phenylcarbamic acid phenylmethyl ester

Chemical Property:

• Vapor Pressure: 0.000234mmHg at 25°C
• Refractive Index: 1.621
• Boiling Point: 325.2 °C at 760 mmHg
• Flash Point: 150.5 °C
• PSA: 38.33000
• Density: 1.198 g/cm³
• LogP: 3.50830

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phenylcarbamic acid phenylmethyl ester

There total 55 articles about Phenylcarbamic acid phenylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phenyl isocyanate (103-71-9) + benzyl alcohol (100-51-6,185532-71-2) → N-(benzyloxycarbonyl)aniline (3422-02-4)

Guidance literature:

With MoCl₂O₂(dmf)2; In dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1055/s-0030-1258552

Reference yield: 100.0%

benzyl chloroformate (501-53-1,94274-21-2) + aniline (62-53-3) → N-(benzyloxycarbonyl)aniline (3422-02-4)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; at 0 - 20 ℃;

DOI:10.1021/ol801860s

Reference yield: 98.0%

carbon dioxide (124-38-9,18923-20-1) + benzyl chloride (100-44-7) + aniline (62-53-3) → N-(benzyloxycarbonyl)aniline (3422-02-4)

Guidance literature:

carbon dioxide; aniline; With tetra-(n-butyl)ammonium iodide; caesium carbonate; In N,N-dimethyl-formamide; at 23 ℃; for 1h;

benzyl chloride; In N,N-dimethyl-formamide; at 23 ℃; for 5h;

DOI:10.1016/S0040-4020(02)00286-7

upstream raw materials:

phenyl isocyanate

benzyl chloroformate

aniline

bis(diphenyl)urea

Downstream raw materials:

N'-phenyl-N,N-bis(phenylmethyl)urea

N-Phenyl-N-stearoyl-benzylcarbamat

N-(benzyloxycarbonyl)-N-(2-fluoroethyl)aniline

cyclohexylamine

Refernces

• 1、 Wang, Song-Ning,Zhang, Guo-Yu,Shoberu, Adedamola,Zou, Jian-Ping. "Copper-Catalyzed Coupling of Amines with Carbazates: An Approach to Carbamates". . p. 9067 - 9075. Retrieved 2021/07/19.
• 2、 Mudithanapelli, Chandrashekar,Kim, Mi-Hyun. "Metal-free late-stage C(sp2)-H functionalization of: N -aryl amines with various sodium salts". . p. 450 - 464. Retrieved 2020/02/03.