Methyl 2-acetoxypropanoate

Base Information

• Chemical Name: Methyl 2-acetoxypropanoate
• CAS No.: 6284-75-9
• Molecular Formula: C6H10 O4
• Molecular Weight: 146.143
• NSC Number: 5219
• DSSTox Substance ID: DTXSID40277951
• Nikkaji Number: J651.278J
• Mol file: 6284-75-9.mol

Synonyms:methyl 2-acetoxypropanoate;methyl 2-acetyloxypropanoate;6284-75-9;Methyl (2R)-2-(acetyloxy)propanoate;NSC5219;SCHEMBL866170;methyl (+)-2-acetoxypropanoate;DTXSID40277951;BCP34497;BCP34499;NSC 5219;NSC-5219;2-Acetoxypropionic acid methyl ester;(R)-O-Acetyllactic acid Methyl Ester;BS-47879;CS-0161286;E75438

Chemical Property of Methyl 2-acetoxypropanoate

Chemical Property:

• Vapor Pressure: 1.34mmHg at 25°C
• Refractive Index: 1.4310 (estimate)
• Boiling Point: 172.4°C at 760 mmHg
• Flash Point: 77.2°C
• PSA: 52.60000
• Density: 1.083g/cm³
• LogP: 0.11100
• Water Solubility.: 81.2g/L(25 oC)
• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 146.05790880
• Heavy Atom Count: 10
• Complexity: 141

Purity/Quality:

99% ^*data from raw suppliers

Methyl2-acetoxypropanoate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)OC)OC(=O)C

Technology Process of Methyl 2-acetoxypropanoate

There total 16 articles about Methyl 2-acetoxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic acid methyl ester (79-20-9) + acetic acid (64-19-7,77671-22-8) + D,L-lactide (95-96-5,26680-10-4,26969-66-4,615-95-2) → 2-acetoxypropionic acid (535-17-1) + methyl 2-acetoxypropionate (6284-75-9)

Guidance literature:

With 10H-phenothiazine; nickel diacetate; nickel(II) nitrate; at 225 ℃; for 4h; under 26618.1 Torr; Autoclave;

Reference yield:

methyl lactate (547-64-8,2155-30-8) + sulfuric acid (7664-93-9) + acetic acid (64-19-7,77671-22-8) + toluene (108-88-3,15644-74-3,16713-13-6) → 2-acetoxypropionic acid (535-17-1) + methyl 2-acetoxypropionate (6284-75-9)

Guidance literature:

at 70 - 116 ℃; Einfluss der Schwefelsaeuremenge und des Loesungsmittels auf die Umsetzung;

Reference yield:

methyl lactate (547-64-8,2155-30-8) + sulfuric acid (7664-93-9) + acetic acid (64-19-7,77671-22-8) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → 2-acetoxypropionic acid (535-17-1) + methyl 2-acetoxypropionate (6284-75-9)

Guidance literature:

at 70 - 116 ℃; Einfluss der Schwefelsaeuremenge und des Loesungsmittels auf die Umsetzung;

upstream raw materials:

methanol

2-acetoxypropionic acid

LACTIC ACID

acetic acid methyl ester

Downstream raw materials:

acrylic acid methyl ester

acetic acid

LACTIC ACID

methyl lactate

Refernces

• 1、 -. "Acrylic Acid from Lactide and Process". Page/Page column 3. . Retrieved 2012/04/05.
• 2、 Ooka, Hirohito,Inone, Tsutomu,Itsuno, Shinichi,Tanaka, Masato. "Highly active and selective palladium catalyst for hydroesterification of styrene and vinyl acetate promoted by polymeric sulfonic acids". . p. 1173 - 1175. Retrieved 2007/10/03.