Piperolactam A

Base Information Edit

Chemical Name:Piperolactam A
CAS No.:112501-42-5
Molecular Formula:C₁₆H₁₁NO₃
Molecular Weight:265.268
Hs Code.:
UNII:CXQ3T84KLC
DSSTox Substance ID:DTXSID90150083
Nikkaji Number:J790.693E
Wikipedia:Piperolactam_A
Wikidata:Q72443757
Metabolomics Workbench ID:45875
ChEMBL ID:CHEMBL387864
Mol file:112501-42-5.mol

Synonyms:aristolactam F1;piperolactam A

Suppliers and Price of Piperolactam A

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
AristolactamFI ≥98%
5mg
$ 463.00

Total 14 raw suppliers

Chemical Property of Piperolactam A Edit

Chemical Property:

Vapor Pressure:5.68E-09mmHg at 25°C
Melting Point:>300 °C
Refractive Index:1.776
Boiling Point:457 °C at 760 mmHg
PKA:8.39±0.20(Predicted)
Flash Point:230.2 °C
PSA：62.32000
Density:1.441 g/cm³
LogP:2.98650
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:265.07389321
Heavy Atom Count:20
Complexity:413

Purity/Quality:

98%min ^*data from raw suppliers

AristolactamFI ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C2=C3C(=C1)C(=O)NC3=CC4=CC=CC=C42)O

Technology Process of Piperolactam A

There total 2 articles about Piperolactam A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 53948-09-7
aristololactam BII

: 112501-42-5
piperolactam A

Guidance literature:: With lithium chloride; In N,N-dimethyl-formamide; at 150 ℃; for 12h;
DOI:10.1021/acs.orglett.8b03409

Reference yield:

: C₉H₈BrNO₃

: 40138-16-7
2-formylbenzene boronic acid

: 112501-42-5
piperolactam A

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In ethanol; toluene; at 150 ℃; for 0.166667h; Microwave irradiation;
DOI:10.1016/j.bmcl.2009.04.020