Furodazole

Base Information

• Chemical Name: Furodazole
• CAS No.: 56119-96-1
• Molecular Formula: C₁₅H₁₁N₃O₂
• Molecular Weight: 265.271
• Mol file: 56119-96-1.mol

Synonyms:Furodazole;NSC 225227

Chemical Property of Furodazole

Chemical Property:

• Vapor Pressure: 1.15E-10mmHg at 25°C
• Melting Point: 280-282 °C(Solv: nitromethane (75-52-5))
• Boiling Point: 513.7°C at 760 mmHg
• PKA: 3.54±0.30(Predicted)
• Flash Point: 264.5°C
• PSA: 74.94000
• Density: 1.368g/cm³
• LogP: 3.38510

Purity/Quality:

95-99% ^*data from raw suppliers

FURODAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Anthelmintic.

Technology Process of Furodazole

There total 4 articles about Furodazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-[[2-(2-furyl)-5-benzimidazolyl]amino]crotonate → 2-furan-2-yl-7-methyl-1(3),6-dihydro-imidazo[4,5-f]quinolin-9-one (56119-96-1)

Guidance literature:

Reference yield:

3-(2-furan-2-yl-1(3)H-benzoimidazol-5-ylamino)-but-2-enoic acid ethyl ester (56120-03-7) → 2-furan-2-yl-7-methyl-1(3),6-dihydro-imidazo[4,5-f]quinolin-9-one (56119-96-1)

Guidance literature:

at 230 ℃;

DOI:10.1021/jm00201a014

Reference yield:

2-(2-furyl)-6-nitrobenzimidazole (27146-12-9) → 2-furan-2-yl-7-methyl-1(3),6-dihydro-imidazo[4,5-f]quinolin-9-one (56119-96-1)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) H₂, Raney-Ni, iPrOH, (ii) /BRN= 385838/, CaSO₄, AcOH

2: 230 °C

DOI:10.1021/jm00201a014

upstream raw materials:

3-(2-furan-2-yl-1⁽³⁾H-benzoimidazol-5-ylamino)-but-2-enoic acid ethyl ester

2-(2-furyl)-6-nitrobenzimidazole

Refernces