Leukoflavin

Base Information

• Chemical Name: Leukoflavin
• CAS No.: 13345-95-4
• Molecular Formula: C17H22N4O6
• Molecular Weight: 378.385
• Mol file: 13345-95-4.mol

Synonyms:RFH2;

Chemical Property of Leukoflavin

Chemical Property:

• PSA: 167.36000
• LogP: -1.24680

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Leukoflavin

There total 4 articles about Leukoflavin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

NADH (58-68-4,443892-10-2) + riboflavin (83-88-5,42880-33-1) → RFH2 (13345-95-4) + NAD (53-84-9,66844-06-2)

Guidance literature:

With NaOH-KH₂PO₄ buffer; In water; at 25 ℃; Rate constant; pH 7.0, μ=0.1 mol dm^-3;

Reference yield:

riboflavin → RFH2 (13345-95-4) + riboflavin (83-88-5,42880-33-1)

Guidance literature:

In phosphate buffer; at 22 ℃; pH=7.0; Kinetics;

DOI:10.1021/ja993412k

Reference yield:

L-selenocysteine (3614-08-2,10236-58-5,18312-66-8,176300-66-6) + riboflavin (83-88-5,482-11-1,482-12-2,3687-62-5,5978-87-0,13123-37-0,33210-89-8,35919-91-6,53187-51-2,53187-52-3,135681-43-5,42880-33-1) → 1,5-dihydro-riboflavin (13345-95-4,78692-23-6) + seleno-L-cystine (1464-43-3,2897-21-4,26932-45-6,29621-88-3)

Guidance literature:

In aq. phosphate buffer; at 25 ℃; for 6h; pH=7; pH-value; Equilibrium constant;

DOI:10.1002/kin.21430

upstream raw materials:

NADH

riboflavin

1-Benzyl-1,4-dihydronicotinamide

L-selenocysteine

Downstream raw materials:

L-selenocysteine

riboflavin

riboflavin

Refernces

• 1、 Dobbing, A. Mark,Borman, Christopher D.,Twitchett, Mark B.,Leese, David N.,Salmon, G. Arthur,Sykes, A. Geoffrey. "Mechanistic implications of a linear free-energy correlation of rate constants for the reduction of active- and Met-R2 forms of E. coli ribonucleotide reductase with eight organic radicals". . p. 2206 - 2212. Retrieved 2007/10/03.