3',6'-diethoxyfluorescein

Base Information

• Chemical Name: 3',6'-diethoxyfluorescein
• CAS No.: 21934-70-3
• Molecular Formula: C24H20 O5
• Molecular Weight: 388.42
• Mol file: 21934-70-3.mol

Synonyms:Fluoran,3',6'-diethoxy- (8CI); 3',6'-Diethoxyfluoran; Di-O-ethylfluorescein

Chemical Property of 3',6'-diethoxyfluorescein

Chemical Property:

• Boiling Point: 574.8°Cat760mmHg
• Flash Point: 251.3°C
• PSA: 53.99000
• Density: 1.34g/cm³
• LogP: 5.05200

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3',6'-diethoxyfluorescein

There total 6 articles about 3',6'-diethoxyfluorescein which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethyl bromide (74-96-4) + fluorescein (2321-07-5,126605-73-0) → 3',6'-Diethoxyfluorescein (21934-70-3)

Guidance literature:

fluorescein; With sodium hydroxide; In N,N-dimethyl-formamide; for 2h;

ethyl bromide; With sodium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 8h; Temperature;

Reference yield: 15.2%

phthalic anhydride (85-44-9) + O-ethyl resorcinol (621-34-1) → 3',6'-Diethoxyfluorescein (21934-70-3)

Guidance literature:

With zinc(II) chloride; at 150 - 180 ℃;

Reference yield:

→ 3',6'-Diethoxyfluorescein (21934-70-3) + fluorescein (2321-07-5,126605-73-0)

Guidance literature:

With hydrogenchloride; acetic acid; at 160 ℃; unter Druck;

upstream raw materials:

fluorescein

ethyl bromide

phthalic anhydride

O-ethyl resorcinol

Refernces