Isodihydrofutoquinol A

Base Information

• Chemical Name: Isodihydrofutoquinol A
• CAS No.: 62560-95-6
• Molecular Formula: C₂₁H₂₄O₅
• Molecular Weight: 356.419
• Mol file: 62560-95-6.mol

Synonyms:

Chemical Property of Isodihydrofutoquinol A

Chemical Property:

• PSA: 53.99000
• LogP: 3.59460

Purity/Quality:

98.5% ^*data from raw suppliers

IsodihydrofutoquinolA 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isodihydrofutoquinol A

There total 5 articles about Isodihydrofutoquinol A which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

methanol (67-56-1) + 2-Allyl-4-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-5-methoxy-phenol (62499-73-4,104973-93-5) → C20H20O4 + 6-Allyl-4-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-3,6-dimethoxy-cyclohexa-2,4-dienone (104865-73-8) + isodihydrofutoquinol A (62499-71-2,62560-95-6,74163-93-2,74163-94-3,104973-89-9)

Guidance literature:

In tetrahydrofuran; electrochemical method;

DOI:10.1016/S0040-4039(00)94967-0

Reference yield:

2-(3,4-methylenedioxyphenyl)-1,3-dithiane (56579-86-3) → isodihydrofutoquinol A (62499-71-2,62560-95-6,74163-93-2,74163-94-3,104973-89-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / n-BuLi / tetrahydrofuran / 1 h / -70 - -20 °C

2: 78 percent / Raney Ni / dioxane / 20 h / Heating

3: 1.) K₂CO₃ / 1.) acetone, reflux, 11 h, 2.) 125 grad C, 4 h

4: 51 percent / tetrahydrofuran / electrolyzis, glassy carbon anode, platinum cathode

With n-butyllithium; nickel; potassium carbonate; In tetrahydrofuran; 1,4-dioxane;

DOI:10.1016/S0040-4039(00)94967-0

Reference yield:

1-(4-(benzyloxy)-2-methoxyphenyl)ethanone (56879-12-0) → isodihydrofutoquinol A (62499-71-2,62560-95-6,74163-93-2,74163-94-3,104973-89-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 93 percent / n-BuLi / tetrahydrofuran / 1 h / -70 - -20 °C

2: 78 percent / Raney Ni / dioxane / 20 h / Heating

3: 1.) K₂CO₃ / 1.) acetone, reflux, 11 h, 2.) 125 grad C, 4 h

4: 51 percent / tetrahydrofuran / electrolyzis, glassy carbon anode, platinum cathode

With n-butyllithium; nickel; potassium carbonate; In tetrahydrofuran; 1,4-dioxane;

DOI:10.1016/S0040-4039(00)94967-0

upstream raw materials:

methanol

2-Allyl-4-(2-benzo[1,3]dioxol-5-yl-1-methyl-ethyl)-5-methoxy-phenol

2-(3,4-methylenedioxyphenyl)-1,3-dithiane

1-(4-(benzyloxy)-2-methoxyphenyl)ethanone

Downstream raw materials:

futoquinol

Refernces