Isopteleine

Base Information

• Chemical Name: Isopteleine
• CAS No.: 2181-84-2
• Molecular Formula: C₁₃H₁₁NO₃
• Molecular Weight: 229.235
• Hs Code.: 2934999090
• Mol file: 2181-84-2.mol

Synonyms:6-Methoxyisodictamnine;Isopteleine

Chemical Property of Isopteleine

Chemical Property:

• Melting Point: 210-211℃
• Boiling Point: 399.9±42.0 °C(Predicted)
• PKA: 1.05±0.20(Predicted)
• PSA: 44.37000
• Density: 1.270±0.06 g/cm3(Predicted)
• LogP: 2.29330

Purity/Quality:

98.5% ^*data from raw suppliers

Isopteleine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: The structure of this alkaloid should be as given above.

Technology Process of Isopteleine

There total 8 articles about Isopteleine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-benzyloxy-9H-furo[2,3-b]quinolin-4-one (35307-67-6) → isopteleine (2181-84-2)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HCl / methanol / 10 h / Heating

2: aq. KOH / methanol / 0.5 h

With hydrogenchloride; potassium hydroxide; In methanol;

Reference yield:

6-benzyloxy-3-hydroxy-9H-furo[2,3-b]quinolin-4-one (35307-65-4) → isopteleine (2181-84-2)

Guidance literature:

Multi-step reaction with 3 steps

1: NaBH₄, NaOH / methanol

2: aq. HCl / methanol / 10 h / Heating

3: aq. KOH / methanol / 0.5 h

With hydrogenchloride; potassium hydroxide; sodium hydroxide; sodium tetrahydroborate; In methanol;

Reference yield:

3-hydroxy-6-methoxy-9H-furo[2,3-b]quinolin-4-one (74121-02-1) → isopteleine (2181-84-2)

Guidance literature:

Multi-step reaction with 2 steps

1: NaBH₄, aq. NaOH / methanol

With sodium hydroxide; sodium tetrahydroborate; In methanol;

upstream raw materials:

3,3-dimethyl-3H,7H-furo[2,3-b]pyrano[3,2-f]quinolin-11-one

diazomethane

6-methoxy-9H-furo[2,3-b]quinolin-4-one

6-hydroxy-9H-furo[2,3-b]quinolin-4-one