sodium O,O-dimethyl thiophosphate

Base Information

• Chemical Name: sodium O,O-dimethyl thiophosphate
• CAS No.: 23754-87-2
• Molecular Formula: C2H7 O3 P S . Na
• Molecular Weight: 164.097
• Hs Code.: 2920190090
• Mol file: 23754-87-2.mol

Synonyms:Methylsodium phosphorothioate ((MeO)2(NaO)PS) (6CI); Phosphorothioic acid,O,O-dimethyl ester, sodium salt (8CI,9CI); Sodium O,O-dimethylphosphorothioate; Sodium O,O-dimethyl thiophosphate

Chemical Property of sodium O,O-dimethyl thiophosphate

Chemical Property:

• Melting Point: 200 °C (decomp)
• Boiling Point: 172.4°Cat760mmHg
• Flash Point: 58.1°C
• PSA: 83.42000
• Density: g/cm³
• LogP: 1.58480
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Very Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

SodiumO,O-DimethylThiophosphate(Technicalgrade) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium O,O-Dimethyl Thiophosphate is a reactant used in the rearrangement of S-(2-Aminoethyl)thiophosphates to N-(2-Mercaptoethyl)phosphoramidates.

Technology Process of sodium O,O-dimethyl thiophosphate

There total 6 articles about sodium O,O-dimethyl thiophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.31%

Dimethyl phosphite (868-85-9) → Natriumsalz des Thiophosphorsaeure-O,O-dimethylesters (23754-87-2)

Guidance literature:

Dimethyl phosphite; With sodium; In methanol; at 40 ℃; for 0.333333h;

With sulfur; In methanol; at 50 ℃; for 5h;

Reference yield: 95.0%

dibenzoyl disulfide (644-32-6) + Dimethyl phosphite (868-85-9) → benzoyl sulfide (1850-15-3) + Natriumsalz des Thiophosphorsaeure-O,O-dimethylesters (23754-87-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 1,2-dichloro-ethane; at 20 ℃; for 0.5h;

DOI:10.1016/S0040-4039(00)70669-1

Reference yield:

methyl phosphite (96-36-6,868-85-9) → Natriumsalz des Thiophosphorsaeure-O,O-dimethylesters (23754-87-2)

Guidance literature:

With sodium methylate; sulfur; Yield given. Multistep reaction; 1.) methanol, diethyl ether, 20 min, 2.) reflux;

DOI:10.1016/0022-328X(90)87145-4

upstream raw materials:

methyl phosphite

cyanophos

O-(4-cyano-2-methylphenyl) O,O-dimethyl phosphorothioate

dibenzoyl disulfide

Downstream raw materials:

O,O,S-trimethyl phosphorothioate

omethoate

O,O'-dimethylmonothiophosphatotriphenyltin(IV)

Thiophosphoric acid S-cyclohexylethynyl ester O,O'-dimethyl ester

Refernces

• 1、 Chen, Menglin,Maetzke, Alice,Knak Jensen, Svend J.,Gothelf, Kurt V.. "Rearrangement of S-(2-aminoethyl) thiophosphates to N-(2-mercaptoethyl)- phosphoramidates". . p. 5826 - 5833. Retrieved 2008/04/13.
• 2、 Masters, J. G.,Nasser, F. A. K.,Hossain, M. B.,Hagen, A. P.,Helm, D. van der,Zuckerman, J. J.. "Oxy- and thio-phosphorus acid derivatives of tin(IV). The crystal and molecular structure of O-methylmethylphosphatotriphenyltin(IV)". . p. 39 - 48. Retrieved 2007/10/02.