Tyrphostin A25

Base Information Edit

Chemical Name:Tyrphostin A25
CAS No.:118409-58-8
Deprecated CAS:158129-55-6
Molecular Formula:C10H6N2O3
Molecular Weight:202.169
Hs Code.:
NSC Number:676484
UNII:C878BF87UY
DSSTox Substance ID:DTXSID4045216
Nikkaji Number:J397.954G
Wikidata:Q27163858
NCI Thesaurus Code:C1484
ChEMBL ID:CHEMBL310798
Mol file:118409-58-8.mol

Synonyms:(3,4,5-trihydroxybenzylidene)-malononitrile;tyrphostin 25;tyrphostin A25;tyrphostin-25

Suppliers and Price of Tyrphostin A25

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Tyrphostin 25
25mg
$ 425.00

TRC
Tyrphostin25
5mg
$ 50.00

Sigma-Aldrich
AG 82
5mg
$ 66.90

Medical Isotopes, Inc.
Tyrphostin25
125 mg
$ 2000.00

Cayman Chemical
AG 82 ≥95%
25mg
$ 95.00

Cayman Chemical
AG 82 ≥95%
10mg
$ 40.00

Cayman Chemical
AG 82 ≥95%
5mg
$ 21.00

Cayman Chemical
AG 82 ≥95%
50mg
$ 168.00

ApexBio Technology
AG 82
25mg
$ 131.00

ApexBio Technology
AG 82
50mg
$ 233.00

Total 14 raw suppliers

Chemical Property of Tyrphostin A25 Edit

Chemical Property:

Appearance/Colour:Yellow green powder
Vapor Pressure:1.18E-10mmHg at 25°C
Melting Point:-220oC dec.
Refractive Index:1.742
Boiling Point:500.8 °C at 760 mmHg
PKA:7.10±0.23(Predicted)
Flash Point:256.7 °C
PSA：108.27000
Density:1.569 g/cm³
LogP:1.23396
Storage Temp.:2-8°C
Solubility.:DMSO: >50 mg/mL, clear, yellow to orange
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:202.03784206
Heavy Atom Count:15
Complexity:329

Purity/Quality:

98%Min ^*data from raw suppliers

Tyrphostin 25 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C=C(C(=C1O)O)O)C=C(C#N)C#N
Uses An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 for the autophosphorylation of the EGF-receptor An inhibitor of epidermal growth factor receptor tyrosine kinase activity and has a reported IC50 of 15 μM for the autophosphorylation of the EGF-receptor.

Technology Process of Tyrphostin A25

There total 3 articles about Tyrphostin A25 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%