Glycylasparagine

Base Information

• Chemical Name: Glycylasparagine
• CAS No.: 24667-21-8
• Molecular Formula: C₆H₁₁N₃O₄
• Molecular Weight: 189.171
• Hs Code.: 2924199090
• NSC Number: 523090,203810
• DSSTox Substance ID: DTXSID70901535
• Mol file: 24667-21-8.mol

Synonyms:32729-21-8;glycylasparagine;Nalpha-Glycyl-DL-asparagine;H-Gly-DL-Asn-OH;GLYCYL-DL-ASPARAGINE;4-Amino-2-(2-aminoacetamido)-4-oxobutanoic acid;4-amino-2-[(2-aminoacetyl)amino]-4-oxobutanoic acid;(2R)-4-amino-2-[(2-aminoacetyl)amino]-4-oxobutanoic acid;H-Gly-D-Asn-OH;GN dipeptide;G-N Dipeptide;Glycyl-L-asparagin;NSC203810;L-Glycyl-L-Asparagine;NoName_662;Glycine Asparagine dipeptide;Glycine-Asparagine dipeptide;L-Asparagine, N2-glycyl-;2-(2-aminoacetamido)-3-carbamoylpropanoic acid;SCHEMBL7184807;DTXSID70901535;FUESBOMYALLFNI-UHFFFAOYSA-N;GN;MFCD00038155;NSC523090;STL526040;AKOS009158676;NSC-203810;NSC-523090;AS-67359;CS-0320379;FT-0633963;FT-0695021;FT-0707676;G0117;D90713;A875527

Chemical Property of Glycylasparagine

Chemical Property:

• Vapor Pressure: 2.13E-17mmHg at 25°C
• Refractive Index: 7 ° (C=9, H2O)
• Boiling Point: 628.2 °C at 760 mmHg
• PKA: 2.942(at 25℃)
• Flash Point: 333.8 °C
• PSA: 135.51000
• Density: 1.422 g/cm³
• LogP: -0.81860
• Storage Temp.: -20°C
• Water Solubility.: almost transparency
• XLogP3: -4.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 189.07495584
• Heavy Atom Count: 13
• Complexity: 228

Purity/Quality:

98%,99%, ^*data from raw suppliers

Glycyl-d-asparagine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(C(=O)O)NC(=O)CN)C(=O)N

Technology Process of Glycylasparagine

There total 8 articles about Glycylasparagine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-benzyloxycarbonylglycyl-L-asparagine (974-17-4) → glycyl-L-asparagine (1999-33-3,24667-21-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; water; for 2h;

DOI:10.1007/BF00630258

Reference yield:

-benzylester (896436-37-6) → glycyl-L-asparagine (1999-33-3,24667-21-8)

Guidance literature:

With hydrogen; palladium;

DOI:10.1021/jo01065a038

Reference yield:

→ glycyl-L-asparagine (1999-33-3,24667-21-8)

Guidance literature:

With ammonia;

upstream raw materials:

N²-(N,N-phthaloyl-glycyl)-DL-asparagine

N²-(N,N-phthaloyl-glycyl)-L-asparagine

-benzylester

N-benzyloxycarbonylglycyl-L-asparagine

Downstream raw materials:

((S)-3,6-dioxo-piperazin-2-yl)-acetic acid amide

N-chloroacetyl-DL-aspartic acid

ZThrAsp(OBzl)GlyAsnOH

Refernces

• 1、 -. "Novel substrate peptides". . . Retrieved 2008/06/13.