2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid

Base Information

• Chemical Name: 2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
• CAS No.: 20183-47-5
• Molecular Formula: C36H56O12
• Molecular Weight: 680.833
• Hs Code.: 29389090
• Mol file: 20183-47-5.mol

Synonyms:Tenuifolin;

Chemical Property of 2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid

Chemical Property:

• Melting Point: 201-204℃
• Boiling Point: 853.6±65.0 °C(Predicted)
• PKA: 4.15±0.70(Predicted)
• PSA: 214.44000
• Density: 1.39
• LogP: 2.06570
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly), Pyridine (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

Tenuifolin ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Tenuifolin is a terpenoid with potential to treat Alzheimer’s disease.

Technology Process of 2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid

There total 3 articles about 2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

onjisaponin E (82410-35-3) → (E)-3,4,5-trimethoxy-cinnamic acid (20329-98-0,20329-99-1,90-50-6) + tenuifolin (20183-47-5)

Guidance literature:

With potassium hydroxide; for 2h; Heating;

DOI:10.1248/cpb.30.810

Reference yield:

onjisaponin B → (E)-3-(4-methoxyphenyl)acrylic acid (943-89-5) + tenuifolin (20183-47-5)

Guidance literature:

With potassium hydroxide; for 2h; Heating;

DOI:10.1248/cpb.30.810

Reference yield:

onjisaponin A (82410-33-1) → (E)-3-(4-methoxyphenyl)acrylic acid (943-89-5) + tenuifolin (20183-47-5)

Guidance literature:

With potassium hydroxide; for 2h; Heating;

DOI:10.1248/cpb.30.810

upstream raw materials:

onjisaponin E

onjisaponin A

Refernces