1-(2-Chloroethoxy)propane

Base Information

• Chemical Name: 1-(2-Chloroethoxy)propane
• CAS No.: 42149-74-6
• Molecular Formula: C5H11ClO
• Molecular Weight: 122.595
• Hs Code.: 2909199090
• European Community (EC) Number: 255-685-0
• DSSTox Substance ID: DTXSID90194982
• Nikkaji Number: J208.282I
• Wikidata: Q72449924
• Mol file: 42149-74-6.mol

Synonyms:1-(2-Chloroethoxy)propane;42149-74-6;2-Propoxyethyl chloride;2-Chloroethyl-n-propylether;2-Chloroethyl Propyl Ether;Propane, 1-(2-chloroethoxy)-;EINECS 255-685-0;chloroethoxypropane;2-chloroethylpropylether;2-chloroethylpropyl ether;2-propyloxyethyl chloride;2-chloroethyl n-propyl ether;2-chloroethyl-n-propyl ether;SCHEMBL680603;1-(2-Chloroethoxy)propane #;DTXSID90194982;MFCD00059052;AKOS009156555;2-chloroethyl n-propyl ether, AldrichCPR;BS-32420;C1174;CS-0200392;FT-0613235;EN300-95114;H10822;A825789

Chemical Property of 1-(2-Chloroethoxy)propane

Chemical Property:

• Appearance/Colour: Colourless liquid
• Vapor Pressure: 13.7mmHg at 25°C
• Melting Point: -60 °C
• Refractive Index: 1.4157-1.4177
• Boiling Point: 127.2 °C at 760 mmHg
• Flash Point: 42.1 °C
• PSA: 9.23000
• Density: 0.951 g/cm³
• LogP: 1.65180
• Storage Temp.: Flammables area
• Water Solubility.: 6.2 g/L (20 ºC)
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 122.0498427
• Heavy Atom Count: 7
• Complexity: 31.3

Purity/Quality:

99.0% ^*data from raw suppliers

2-PropoxyethylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 41-36/37/38-20/22-10-22
• Safety Statements: 36/37/39-26-16

MSDS Files:

Useful:

• Canonical SMILES: CCCOCCCl

Technology Process of 1-(2-Chloroethoxy)propane

There total 6 articles about 1-(2-Chloroethoxy)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.89%

2-propoxyethanol (2807-30-9) → 2-chloroethyl propyl ether (42149-74-6)

Guidance literature:

With dmap; thionyl chloride; sulfuryl dichloride; at 95 ℃; for 4h; Temperature;

Reference yield: 98.9%

ethylpropylether (628-32-0) → 2-chloroethyl propyl ether (42149-74-6)

Guidance literature:

With pyridine; thionyl chloride; N,N-dimethyl-formamide; at 40 - 95 ℃; for 3h; Temperature;

Reference yield: 98.0%

2-propoxyethyl chloroformate (90512-12-2) → 2-chloroethyl propyl ether (42149-74-6)

Guidance literature:

With dmap; In toluene; at 110 - 125 ℃; for 4h; Reagent/catalyst;

upstream raw materials:

propan-1-ol

N,N-Dichlorobenzenesulfonamide

ethene

2-propoxyethanol

Downstream raw materials:

N-(2-propoxy-ethyl)-aniline

N-(2-propoxyethyl)-2',6'-diethylaniline

4-bromo-2-ethoxy-1-(2-propoxyethoxy)benzene

7-Benzyl-1-(2-propoxyethyl)-3-propylxanthine

Refernces

• 1、 -. "Synthesis process of 2-propoxyethyl chloride". Paragraph 0012; 0017-0032. . Retrieved 2017/08/30.
• 2、 -. "Preparation method of chloro-aliphatic ether". Paragraph 0099; 0112; 0117-0118; 0124; 0129; 0130. . Retrieved 2017/10/13.