3-PYRIDINECARBOXAMIDINE

Base Information

• Chemical Name: 3-PYRIDINECARBOXAMIDINE
• CAS No.: 23255-20-1
• Molecular Formula: C6H7N3
• Molecular Weight: 121.142
• Hs Code.: 2933399090
• Mol file: 23255-20-1.mol

Synonyms:Nicotinamidine(6CI,8CI);3-Pyridinecarboxamidine;

Chemical Property of 3-PYRIDINECARBOXAMIDINE

Chemical Property:

• Melting Point: 190 °C
• Boiling Point: 240.7 °C at 760 mmHg
• PKA: 10.29±0.50(Predicted)
• Flash Point: 99.4 °C
• PSA: 62.76000
• Density: 1.22 g/cm³
• LogP: 1.96770
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-Pyridinecarboxamidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PYRIDINECARBOXAMIDINE

There total 3 articles about 3-PYRIDINECARBOXAMIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine-3-carbonitrile (100-54-9,121697-66-3,1232169-17-3,68271-95-4) → 3-pyridinecarboximidamide (23255-20-1)

Guidance literature:

With hydrogenchloride; ethanol; chloroform; Erwaermen des Reaktionsprodukts in wss. Aethanol mit NH₄Cl;

DOI:10.1021/ja01237a502 DOI:10.1021/ja01588a045

Reference yield:

ethyl (3-pyridyl)imidate dihydrochloride (56624-12-5,81659-46-3) → 3-pyridinecarboximidamide (23255-20-1)

Guidance literature:

With ammonia;

Reference yield:

→ 3-pyridinecarboximidamide (23255-20-1)

Guidance literature:

RCl;

upstream raw materials:

pyridine-3-carbonitrile

ethyl (3-pyridyl)imidate dihydrochloride

Downstream raw materials:

2-[3]pyridyl-7(9)H-purin-6-ylamine

2-(pyridin-3-yl)pyrimidine-5-carbonitrile

2-phenyl-5-(2-(pyridin-3-yl)-1H-imidazol-5-yl)pyrimidine

1-(Imino-pyridin-3-yl-methyl)-3-p-tolyl-thiourea

Refernces

• 1、 Ho, Koc-Kan,Auld, Douglas S.,Bohnstedt, Adolph C.,Conti, Paolo,Dokter, Wim,Erickson, Shawn,Feng, Daming,Inglese, Jim,Kingsbury, Celia,Kultgen, Steven G.,Liu, Rong-Qiang,Masterson, Christopher M.,Ohlmeyer, Michael,Rong, Yajing,Rooseboom, Martijn,Roughton, Andrew,Samama, Philippe,Smit, Martin-Jan,Son, Ellen,van der Louw, Jaap,Vogel, Gerard,Webb, Maria,Wijkmans, Jac,You, Ming. "Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists". . p. 2724 - 2728. Retrieved 2007/10/03.