N-p-CouMaroyloctopaMine

Base Information

• Chemical Name: N-p-CouMaroyloctopaMine
• CAS No.: 66648-45-1
• Molecular Formula: C₁₇H₁₇NO₄
• Molecular Weight: 299.326
• Mol file: 66648-45-1.mol

Synonyms:N-trans-p-coumaroyl octopamine;2,4-NONADIEN-1-AL;N-trans-p-Cumaroyloctopamin;trans-N-p-coumaroyloctopamine;N-trans-coumaroyloctopamine;2,4-NONADIENAL;

Chemical Property of N-p-CouMaroyloctopaMine

Chemical Property:

• Boiling Point: 638.9±55.0 °C(Predicted)
• PKA: 9.76±0.26(Predicted)
• PSA: 89.79000
• Density: 1.329±0.06 g/cm3(Predicted)
• LogP: 2.35170

Purity/Quality:

98% ^*data from raw suppliers

Octopamine, N-p-coumaroyl- ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-p-CouMaroyloctopaMine

There total 3 articles about N-p-CouMaroyloctopaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

octopamine (104-14-3,1915-83-9) + 4-hydroxycinnamic acid N-hydroxysuccinimide ester (88492-43-7) → (–)-trans-N-p-coumaroyl octopamine (88700-34-9,66648-45-1)

Guidance literature:

With sodium hydrogencarbonate; In water; acetone; for 24h;

DOI:10.1016/0031-9422(96)00173-2

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → (–)-trans-N-p-coumaroyl octopamine (88700-34-9,66648-45-1)

Guidance literature:

Multi-step reaction with 2 steps

1: piperidine; pyridine

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate / N,N-dimethyl-formamide

With piperidine; pyridine; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;

DOI:10.1016/j.foodchem.2012.02.152

Reference yield:

octopamine (104-14-3,1915-83-9) + p-Coumaric Acid (7400-08-0,50940-26-6) → (–)-trans-N-p-coumaroyl octopamine (88700-34-9,66648-45-1)

Guidance literature:

With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; In N,N-dimethyl-formamide;

DOI:10.1016/j.foodchem.2012.02.152

upstream raw materials:

octopamine

4-hydroxycinnamic acid N-hydroxysuccinimide ester

p-Coumaric Acid

4-hydroxy-benzaldehyde

Downstream raw materials:

triacetyl N-trans-p-coumaroyl octopamine

Refernces

• 1、 Muehlenbeck, Ute,Kortenbusch, Albertus,Barz, Wolfgang. "Formation of hydroxycinnamoylamides and α-hydroxyacetovanillone in cell cultures of Solanum khasianum". . p. 1573 - 1579. Retrieved 2007/10/03.