oxazolo[4,5-b]pyridin-2(3H)-one

Base Information Edit

Chemical Name:oxazolo[4,5-b]pyridin-2(3H)-one
CAS No.:60832-72-6
Molecular Formula:C6H4N2O2
Molecular Weight:136.11
Hs Code.:2934999090
European Community (EC) Number:676-201-8
DSSTox Substance ID:DTXSID50209667
Nikkaji Number:J1.526.299K
Wikidata:Q27117908
Metabolomics Workbench ID:55916
ChEMBL ID:CHEMBL329270
Mol file:60832-72-6.mol

Synonyms:oxazolo[4,5-b]pyridin-2(3H)-one;60832-72-6;3H-Oxazolo[4,5-b]pyridin-2-one;2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one;[1,3]oxazolo[4,5-b]pyridin-2-ol;3H-[1,3]oxazolo[4,5-b]pyridin-2-one;Oxazolo(4,5-b)pyridin-2(3H)-one;[1,3]oxazolo[4,5-b]pyridin-2(3H)-one;MFCD00204215;CHEMBL329270;2H,3H-[1,3]oxazolo[4,5-b]pyridin-2-one;CHEBI:38580;SCHEMBL340652;2-oxooxazolo[4,5-b]pyridine;oxazolo[4,5-b]pyridin-2-one;SCHEMBL22221895;DTXSID50209667;OVLXOTUWFLHWQT-UHFFFAOYSA-N;BCP10943;BDBM50290808;Oxazolo[4,5-b]pyridine-2(3H)-one;AKOS006229689;AKOS015855703;AS-5312;2,3-Dihydropyrido[2,3-d][1,3]oxaz;AC-24171;CS-10384;SY007988;A8468;AM20061876;CS-0012220;FT-0601106;O0408;EN300-93029;[1,3]oxazolo[4,5-b]pyridin-2-ol, AldrichCPR;W-200556;Q27117908;2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one, AldrichCPR

Suppliers and Price of oxazolo[4,5-b]pyridin-2(3H)-one

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one
50g
$ 950.00

TCI Chemical
Oxazolo[4,5-b]pyridin-2(3H)-one
5G
$ 84.00

TCI Chemical
Oxazolo[4,5-b]pyridin-2(3H)-one
25G
$ 251.00

SynQuest Laboratories
2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one
5 g
$ 480.00

SynQuest Laboratories
2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one
1 g
$ 128.00

Matrix Scientific
Oxazolo[4,5-b]pyridin-2(3H)-one 95+%
1g
$ 36.00

Matrix Scientific
Oxazolo[4,5-b]pyridin-2(3H)-one 95+%
5g
$ 95.00

Matrix Scientific
Oxazolo[4,5-b]pyridin-2(3H)-one 95+%
10g
$ 143.00

Crysdot
Oxazolo[4,5-b]pyridin-2(3H)-one 97%
100g
$ 108.00

Chem-Impex
Oxazolo[4,5-b]pyridin-2(3H)-one,≥98%(GC) ≥98%(GC)
25G
$ 286.58

Total 100 raw suppliers

Chemical Property of oxazolo[4,5-b]pyridin-2(3H)-one Edit

Chemical Property:

Appearance/Colour:White or light yellow crystalline powder
Melting Point:214 °C
Refractive Index:1.595
Boiling Point:253.8±23.0 °C(Predicted)
PKA:2.76±0.20(Predicted)
PSA：58.89000
Density:1.428 g/cm³
LogP:0.51610
Storage Temp.:Refrigerator
Solubility.:DMSO, Methanol
XLogP3:0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:136.027277375
Heavy Atom Count:10
Complexity:160

Purity/Quality:

99% ^*data from raw suppliers

2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn,Xi
Statements: 20/21/22-36/37/38-36-22
Safety Statements: 22-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(NC(=O)O2)N=C1
Uses 2,3-Dihydropyrido[2,3-d][1,3]oxazol-2-one is a benzoxazolone analogue that may be used to inhibit the nitric oxide synthases (NOS).

Technology Process of oxazolo[4,5-b]pyridin-2(3H)-one

There total 22 articles about oxazolo[4,5-b]pyridin-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 16867-03-1
2-amino-3-hydroxypyridine

: 201230-82-2
carbon monoxide

: 60832-72-6
2,3-dihydro[1,3]oxazolo[4,5-b]pyridin-2-one

Guidance literature:: With oxygen; potassium iodide; palladium(II) iodide; at 100 ℃; for 24h; under 15001.5 Torr; Autoclave;
DOI:10.1002/cssc.201500343