2-[(Ammonioacetyl)amino]propanoate

Base Information

• Chemical Name: 2-[(Ammonioacetyl)amino]propanoate
• CAS No.: 926-77-2
• Molecular Formula: C5H10 N2 O3
• Molecular Weight: 146.146
• Hs Code.: 2924199090
• Mol file: 926-77-2.mol

Synonyms:2-[(ammonioacetyl)amino]propanoate;2-[(2-azaniumylacetyl)amino]propanoate;BDBM50137049

Chemical Property of 2-[(Ammonioacetyl)amino]propanoate

Chemical Property:

• Melting Point: 235 °C
• Boiling Point: 417.4±30.0 °C(Predicted)
• PKA: 3.16±0.10(Predicted)
• PSA: 92.42000
• Density: 1.263±0.06 g/cm3(Predicted)
• LogP: -0.37440
• Storage Temp.: −20°C
• Water Solubility.: almost transparency in Water
• XLogP3: -3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 146.06914219
• Heavy Atom Count: 10
• Complexity: 140

Purity/Quality:

98%,99%, ^*data from raw suppliers

Glycyl-DL-alanine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)[O-])NC(=O)C[NH3+]
• Uses: Glycyl-DL-alanine is used in method for separating chiral Amino Acid by liquid chromatography.

Technology Process of 2-[(Ammonioacetyl)amino]propanoate

There total 14 articles about 2-[(Ammonioacetyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycyl=>leucyl=>glycyl=>alanine + furan-2,3,5(4H)-trione pyridine (1:1) → glycylalanine (926-77-2,2325-50-0) + glycine (56-40-6,18875-39-3,25718-94-9) + LEUCINE (328-39-2,21675-61-6,25248-98-0,70-45-1)

Guidance literature:

at 37 ℃; glycyl-l-leucyl-glycyl-l-alanine;

Reference yield:

leucyl=>glycyl=>alanine + furan-2,3,5(4H)-trione pyridine (1:1) → glycylalanine (926-77-2,2325-50-0) + LEUCINE (328-39-2,21675-61-6,25248-98-0,70-45-1)

Guidance literature:

-glycyl-l-alanine;

Reference yield:

GlyGlyAla (14390-29-5,855529-09-8) → glycylalanine (926-77-2,2325-50-0) + glycine (56-40-6,18875-39-3,25718-94-9)

Guidance literature:

With deuteriated sodium hydroxide; dihydrogen peroxide; water-d2; at 37 ℃; Kinetics;

DOI:10.1021/ol035811x

upstream raw materials:

monochloroacetyl-DL-alanine

N-(N-benzyloxycarbonyl-glycyl)-DL-alanine

glycyl-L-alanine

Gly-L-Ala

Downstream raw materials:

N-(N-acetylthiocarbamoyl-glycyl)-alanine

3-methylpiperazine-2,5-dione

GlyGlyAla

2-[(1-(4-Dimethylamino-phenyl)-3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-2-{6-[2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-acetoxy]-2,7-dimethoxy-1,4-dioxo-1,4-dihydro-carbazol-9-yl}-4-oxo-azetidine-2-carbonyl)-amino]-propionic acid

Refernces

• 1、 Smith, Grant Gill,Evans, Robert C.,Baum, Rocky. "Neighboring Residue Effects: Evidence for Intramolecular Assistance to Racemization or Epimerization of Dipeptide Residues". . p. 7327 - 7332. Retrieved 2007/10/02.