Trimethylphosphine sulfide

Base Information

• Chemical Name: Trimethylphosphine sulfide
• CAS No.: 2404-55-9
• Molecular Formula: C3H9PS
• Molecular Weight: 108.144
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID10178784
• Nikkaji Number: J151.299D
• Wikidata: Q83049262
• ChEMBL ID: CHEMBL5190639
• Mol file: 2404-55-9.mol

Synonyms:Trimethylphosphine sulfide;2404-55-9;Phosphine sulfide, trimethyl-;trimethyl(sulfanylidene)-lambda5-phosphane;Me3PS;SCHEMBL768468;CHEMBL5190639;phosphorane, trimethyl-, sulfide;DTXSID10178784;KTFAZNVGJUIWJM-UHFFFAOYSA-N;FT-0634251;InChI=1/C3H9PS/c1-4(2,3)5/h1-3H;Phosphine sulfide,trimethyl-(6ci,7ci,8ci,9ci)

Chemical Property of Trimethylphosphine sulfide

Chemical Property:

• Appearance/Colour: White crystalline
• Vapor Pressure: 22.8mmHg at 25°C
• Melting Point: 155-156 ºC
• Refractive Index: 1.458
• Boiling Point: 115.2 ºC at 760 mmHg
• Flash Point: 23.5 ºC
• PSA: 41.90000
• Density: 0.982 g/cm³
• LogP: 2.00590
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 108.01625846
• Heavy Atom Count: 5
• Complexity: 53

Purity/Quality:

98%Min ^*data from raw suppliers

TRIMETHYLPHOSPHINE SULFIDE 97.00% ^*data from reagent suppliers

Safty Information:

• Statements: 11-20/21/22
• Safety Statements: 16-22-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP(=S)(C)C

Technology Process of Trimethylphosphine sulfide

There total 20 articles about Trimethylphosphine sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

trimethylphosphane (594-09-2) → trimethylphosphane sulfide (2404-55-9)

Guidance literature:

With sulfur; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Cooling with ice; Sealed tube;

DOI:10.1002/anie.201804072

Reference yield: 91.0%

sulfur (10544-50-0) + tetrakis(trimethylphosphine)cobalt(0) (33152-37-3) → di-μ-sulfidobis{tris(trimethylphosphine)cobalt} + trimethylphosphane sulfide (2404-55-9)

Guidance literature:

In pentane; Ar atmosphere, stirring (0°C, 1 h; 20°C, 2 h), sepn. of Me3PS (filtration off); crystn. on cooling (dry ice); elem. anal.;

Reference yield: 80.0%

sulfur (10544-50-0) + bis(trimethylphosphane)dichloridoplatinum(II) (21545-76-6,19471-47-7,15630-86-1) → PtS4(P(CH3)3)2 (121872-70-6) + trimethylphosphane sulfide (2404-55-9)

Guidance literature:

With NH₃; In ammonia; NH3 (liquid); inert atmosphere;

upstream raw materials:

diethyl ether

dithiocarboxy-trimethyl-phosphonium betaine

methyllithium

tetramethylphosphonium hydroxide

Downstream raw materials:

Trimethylphosphine oxide

((((2,6-di(isopropyl)phenyl)N)2C3HMe2)iron(II))2(μ-S)

[(Fe(H₃CC(C(CH₃)NC₆H₃(CH(CH₃)2)2)2))2(S)]

hydrogen

Refernces

• 1、 Durgaprasad, Gummadi,Xie, Zhu-Lin,Rose, Michael J.. "Iron Hydride Detection and Intramolecular Hydride Transfer in a Synthetic Model of Mono-Iron Hydrogenase with a CNS Chelate". . p. 386 - 389. Retrieved 2016.
• 2、 Morgan, M. Thomas,Yang, Bo,Harankhedkar, Shefali,Nabatilan, Arielle,Bourassa, Daisy,McCallum, Adam M.,Sun, Fangxu,Wu, Ronghu,Forest, Craig R.,Fahrni, Christoph J.. "Stabilization of Aliphatic Phosphines by Auxiliary Phosphine Sulfides Offers Zeptomolar Affinity and Unprecedented Selectivity for Probing Biological CuI". . p. 9711 - 9715. Retrieved 2018.
• 3、 Garcia-Rodriguez, Raul,Liu, Haitao. "Mechanistic study of the synthesis of CdSe nanocrystals: Release of selenium". supporting information; experimental part. p. 1400 - 1403. Retrieved 2012/03/12.