(+)-Selegiline

Base Information Edit

Chemical Name:(+)-Selegiline
CAS No.:4528-51-2
Molecular Formula:C₁₃H₁₇N
Molecular Weight:187.285
Hs Code.:
UNII:YK7HY2RY1W
DSSTox Substance ID:DTXSID901317215
Nikkaji Number:J548.761G
Wikipedia:D-Deprenyl
Wikidata:Q5203251
Pharos Ligand ID:4ZNNQA7DYMDQ
ChEMBL ID:CHEMBL16857
Mol file:4528-51-2.mol

Synonyms:(+)-Selegiline;D-Deprenyl;(+)-Deprenyl;S-(+)-Deprenyl;Selegiline, (+)-;UNII-YK7HY2RY1W;YK7HY2RY1W;4528-51-2;CHEMBL16857;Selegiline hydrochloride specified impurity E [EP];Benzeneethanamine, N,alpha-dimethyl-N-2-propyn-1-yl-, (alphaS)-;Lopac-M-003;NCGC00016708-01;CAS-14611-52-0;Lopac0_000842;SCHEMBL12248117;DTXSID901317215;BDBM50535912;CCG-204925;NCGC00015624-01;NCGC00015624-02;NCGC00015624-04;Q5203251;SELEGILINE HYDROCHLORIDE IMPURITY E [EP IMPURITY];(R,S)-Methyl-(1-methyl-2-phenyl-ethyl)-prop-2-ynyl-amine;Benzeneethanamine, N,.alpha.-dimethyl-N-2-propyn-1-yl-, (.alpha.R)-;BENZENEETHANAMINE, N,.ALPHA.-DIMETHYL-N-2-PROPYN-1-YL-, (.ALPHA.S)-

Suppliers and Price of (+)-Selegiline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 45 raw suppliers

Chemical Property of (+)-Selegiline Edit

Chemical Property:

PSA：3.24000
LogP:2.18260
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:187.136099547
Heavy Atom Count:14
Complexity:195

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC=CC=C1)N(C)CC#C
Isomeric SMILES:C[C@@H](CC1=CC=CC=C1)N(C)CC#C

Technology Process of (+)-Selegiline

There total 41 articles about (+)-Selegiline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 14611-52-0,2079-54-1
(R)-(-)-deprenyl hydrochloride

: 2323-36-6,4528-51-2,4530-70-5,14611-51-9
SELEGILINE

Guidance literature:: With sodium carbonate; for 1h;
DOI:10.1016/j.ijpharm.2011.01.015

Reference yield: 85.0%

: 826-10-8,4298-16-2
(R)-2-N-methylamino-1-phenylpropane hydrochloride

: 106-96-7
propargyl bromide

: 2323-36-6,4528-51-2,4530-70-5,14611-51-9
SELEGILINE

Guidance literature:: With potassium carbonate; In toluene; acetonitrile; at 20 ℃; for 3h; enantioselective reaction;
DOI:10.1016/j.tetlet.2015.10.010