2,4-Dimethyl-6-nitroaniline

Base Information Edit

Chemical Name:2,4-Dimethyl-6-nitroaniline
CAS No.:1635-84-3
Molecular Formula:C8H10 N2 O2
Molecular Weight:166.18
Hs Code.:29214990
European Community (EC) Number:216-662-0
NSC Number:9816
UNII:ZF8VRN3SKA
DSSTox Substance ID:DTXSID00167607
Nikkaji Number:J141.319H
Wikidata:Q72470978
Mol file:1635-84-3.mol

Synonyms:2,4-Dimethyl-6-nitroaniline;1635-84-3;4,6-Dimethyl-2-nitroaniline;Benzenamine, 2,4-dimethyl-6-nitro-;6-Nitro-2,4-xylidine;(2,4-dimethyl-6-nitrophenyl)amine;2-nitro-4,6-dimethylaniline;NSC-9816;EINECS 216-662-0;MFCD00007739;NSC9816;2,4-DIMETHYL-6-NITROBENZENAMINE;ZF8VRN3SKA;Cambridge id 5100320;2,4-Xylidine, 6-nitro-;SCHEMBL349045;Benzenamine,4-dimethyl-6-nitro-;DTXSID00167607;2,4-Dimethyl-6-nitro-phenylamine;4,6-Dimethyl-2-nitro-phenylamine;NSC 9816;STL068920;4,6-Dimethyl-2-nitroaniline, 97%;AKOS000504390;AC-4384;BK-0709;CS-W008334;NCGC00325905-01;SY005166;BB 0256688;FT-0633724;EN300-112989;AB01320850-02;AI-346/31791004;4,6-Dimethyl-2-nitroaniline, technical grade, 90%;J-010065

Suppliers and Price of 2,4-Dimethyl-6-nitroaniline

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dimethyl-6-nitroaniline
10g
$ 360.00

Sigma-Aldrich
4,6-Dimethyl-2-nitroaniline 97%
5g
$ 181.00

Sigma-Aldrich
4,6-Dimethyl-2-nitroaniline technical grade, 90%
1g
$ 35.40

Crysdot
2,4-Dimethyl-6-nitroaniline 97%
25g
$ 208.00

ChemScene
2,4-Dimethyl-6-nitroaniline 99.78%
5g
$ 60.00

ChemScene
2,4-Dimethyl-6-nitroaniline 99.78%
10g
$ 97.00

Chemenu
2,4-Dimethyl-6-nitroaniline 95+%
10g
$ 115.00

Chemenu
2,4-Dimethyl-6-nitroaniline 95+%
25g
$ 191.00

Biosynth Carbosynth
(2,4-Dimethyl-6-nitrophenyl)amine
1 g
$ 105.00

Biosynth Carbosynth
(2,4-Dimethyl-6-nitrophenyl)amine
5 g
$ 358.00

Total 41 raw suppliers

Chemical Property of 2,4-Dimethyl-6-nitroaniline Edit

Chemical Property:

Vapor Pressure:0.000346mmHg at 25°C
Melting Point:64-68 °C(lit.)
Boiling Point:319.1°Cat760mmHg
PKA:0.27±0.25(Predicted)
Flash Point:146.8°C
PSA：71.84000
Density:1.22g/cm³
LogP:2.89820
Storage Temp.:Keep in dark place,Sealed in dry,Store in freezer, under -20°C
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:178

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,4-Dimethyl-6-nitroaniline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn,Xi
Statements: 20/21/22-36/37/38
Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1=CC(=C(C(=C1)[N+](=O)[O-])N)C
Uses 2,4-Dimethyl-6-nitroaniline is used as a reagent in the synthetic preparation of 1,2-bis-substituted benzimidazoles as nonnucleoside HIV-1 reverse transcriptase inhibitors.

Technology Process of 2,4-Dimethyl-6-nitroaniline

There total 14 articles about 2,4-Dimethyl-6-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 95-68-1
2,4-Xylidine

: 1635-84-3
2,4-Dimethyl-6-nitroanilin

Guidance literature:: 2,4-Xylidine; With nitric acid; acetic anhydride; at 0 ℃; for 0.5h;

With hydrogenchloride; water; at 0 ℃; for 4h; Heating / reflux;

With ammonia; In water;

Reference yield: 89.0%

: 593255-20-0
2-iodo-3,5-dimethyl-1-nitrobenzene

: 1635-84-3
2,4-Dimethyl-6-nitroanilin

Guidance literature:: With ammonium hydroxide; caesium carbonate; In water; for 3h; Reflux; Green chemistry;
DOI:10.1002/cjoc.201400138

Reference yield: 30.0%

: 95-68-1
2,4-Xylidine

: 1635-84-3
2,4-Dimethyl-6-nitroanilin

: 31167-04-1
(2,4-dimethyl-3-nitro-phenyl)amine

Guidance literature:: With 4-nitro-4-methyl-2,3,5,6-tetrabromo-2,5-cyclohexadien-1-one; In acetic acid; for 3h; Ambient temperature;
DOI:10.1055/s-1989-27387