Synthetic Communications p. 759 - 766 (1994)
Update date:2022-08-11
Topics:
Kuge
Nakazawa
Kometani
Sugaya
Mochida
Tomioka
A one-pot synthesis of vinpocetine from vincamine was established. Lewis acids caused transesterification and/or dehydration of vincamine in EtOH. FeCl3 catalyzed both transesterification and dehydration while Ti(OEt)4 selectively catalyzed transesterification.
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