Journal of Molecular Catalysis B: Enzymatic p. 141 - 146 (2015)
Update date:2022-08-23
Topics:
Xin, XiuLan
Fan, Guang-Jun
Sun, Zheng
Zhang, Ning
Li, Ye
Lan, Rong
Chen, Liang
Dong, PeiPei
Biotransformation of icariin (1), epimedin C (2), epimedoside A (3), epimedin A (4) and epimidin B (5), five major components of E. koreanum, were performed by using Cunninghamella blakesleana. And they could be metabolized efficiently to icariside II (1a), 2″-O-rhamnosylikarisoside II (2a), epimedoside b (3a), baohuoside VII (4a) and sagittatoside B (5a) with high yields of 95.1%, 97.7%, 93.7%, 95.8% and 96.4%, respectively. And these transformed products as major forms of herb epimedii in vivo exhibited the more significant anti-osteoporosis activities. Our method could be applied for enriching these rare flavonoids in herb epimedii, for further development of anti-osteoporosis medicines or functional foods.
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Doi:10.1021/jm00016a011
(1995)Doi:10.1016/00404-0399(50)1427J-
(1995)Doi:10.1111/j.1945-5100.2000.tb01486.x
(1930)Doi:10.1002/chem.201402825
(2014)Doi:10.1246/bcsj.39.2018
(1966)Doi:10.1039/tf9625800230
(1962)