Tetrahedron p. 14233 - 14254 (1998)
Update date:2022-09-26
Topics:
Jiang, Lu
Davison, Amanda
Tennant, George
Ramage, Robert
An optimal coupling reagent, ethyl 1-hydroxy-1H-1,2,3-triazole-4- carboxylate (HOCt), has been designed and synthesised for application to solid phase peptide synthesis using Fmoc chemistry. It is used in combination with carbodiimide reagents, has very high coupling efficiency, and does not absorb at 302nm, thus allowing real-time monitoring of each coupling cycle. Its applications in the synthesis of endothelin analogues and difficult sequences are also discussed.
View MoreSINO Industries Company Limited
Contact:86-29-85369724
Address:No.111, Jiefang Road, Xi’an, China
Contact:86-512-87182056
Address:No.128 Fangzhou Rd, Suzhou Industrial Park, China, 215125, China
SHANXI JINJIN CHEMICAL INDUSTRIAL CO.,LTD
website:http://www.jinjingroup.com
Contact:4009982989
Address:Economic And Technological Development Zone,Hejin?City,Shanxi Province?,China
KINHENG CHEMICAL(SHANGHAI)CO., LTD.
Contact:+8621-60490170
Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.
ShangHai BMG Chemical Co., Ltd
Contact:+86-13524845543
Address:Room 602, no 291 sikai road shanghai
Doi:10.1021/acs.orglett.6b00817
(2016)Doi:10.1021/ja01593a043
(1956)Doi:10.1021/ja00531a024
(1980)Doi:10.1021/jo049794g
(2004)Doi:10.1016/j.tet.2003.11.053
(2004)Doi:10.1016/S0040-4039(00)76313-1
(1968)