Synthetic Communications p. 2301 - 2308 (1991)
Update date:2022-08-04
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Cecchetti
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Schiaffella
Rufloxacin (MF-934) was prepared in one-pot synthesis in 61% yield by treatment of the 2,3,5-trifluoro-4-(4-methyl-1-piperazinyl)-benzoyl acetate, first with N,N-dimethylformamide dimethyl acetal, then with 2-aminoethanethiol, followed by cyclization and
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Doi:10.1021/acs.orglett.6b00120
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