Journal of Organometallic Chemistry p. 97 - 105 (1991)
Update date:2022-08-03
Topics:
Marsella, John A.
The selectivity of reactions of ethylene glycol with primary amines in the presence of RuCl2(PPh3)3 at 120 deg C is highly dependent on the steric nature of the amine.Selectivity to di-amination is favored by smaller alkyl groups on the amine while large amines cleanly yield ethanolamines.This contrasts with the results obtained with secondary amines at this temperature, in which ruthenium-triphenylphosphine catalyst systems always favor mono-amination.In the case of sec-butyl amine, where almost equal amounts of mono- and di-aminated product are obtained, the selecti vity can be shifted to mono-amination by the addition of excess triphenylphosphine.The steric effects seen in these reactions are consistent with standard steric parameters availble from the literature.
View MoreHangzhou Hysen Pharma co.,Ltd.
website:http://www.hysenpharma.cn/
Contact:0086-571-88298791
Address:#701,Gudun Road Hangzhou
Suzhou SuKaiLu Chemical Technology Co., Ltd.
Contact:+86-512-62766020
Address:Floor 4, Building 1, Xinyi Pharmaceutical Valley Wisdom Industrial Park, 415 Changyang Street, Suzhou Industrial Park, Jiangsu Province
Shanghai Boyners Pharmaceutical co., LTD.
Contact:+86-02131329586/02154581719
Address:No.328,1#315,Wuhe Road, Shanghai, ,shanghai,China (Mainland)
website:http://www.lidepharma.com
Contact:+86-25-58409506
Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.
Chengdu D-Innovation Pharmaceutical Co., Ltd
Contact:86-28-85105536
Address:1001, B6, No.88 Keyuan South Road, Chengdu Hi-Tech Zone
Doi:10.1007/s11172-010-0026-2
(2009)Doi:10.1021/j100323a061
(1988)Doi:10.1016/j.tet.2009.01.022
(2009)Doi:10.1016/j.bmcl.2009.01.077
(2009)Doi:10.1021/jo01084a021
(1959)Doi:10.1039/jr9570002767
(1957)