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FOTRIN

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Name

FOTRIN

EINECS N/A
CAS No. 37132-72-2 Density 2.1g/cm3
PSA 94.03000 LogP -0.31700
Solubility N/A Melting Point 121°C
Formula C14H28 N9 O P3 Boiling Point °Cat760mmHg
Molecular Weight 431.357 Flash Point °C
Transport Information N/A Appearance N/A
Safety Experimental teratogenic effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and POx. Risk Codes N/A
Molecular Structure Molecular Structure of 37132-72-2 (Fotretamine) Hazard Symbols N/A
Synonyms

Fotretamine;Fotrin; NSC 216135; Photrin; Photrine

 

FOTRIN Chemical Properties

IUPAC Name:  4-[1,3,3,5,5-pentakis(aziridin-1-yl)-2,4,6-triaza-1λ5,3λ5,5λ5-triphosphacyclohexa-1,3,5-trien-1-yl]morpholine
Synonyms: 2,2,4,4,6-Pentaethylenimino-6-morpholino-cyclotriphosphazatrien ; Fotretamina ; Fotretaminum ; Monomorpholine,pentaethyleneiminotriphosphonitrile ; Photrin ; Photrine ; Photrinum 
Canonical Smiles: n1p(np(np1(N2CCOCC2)N3CC3)(N4CC4)N5CC5)(N6CC6)N7CC7
Surface Tension: 144.9 dyne/cm
Index of Refraction: 2.023
Density: 2.1 g/cm
Molecular Weight: 431.3531 g/mol
Appearance:  white crystalline powder
Solubility: easy soluble in water and alcohol
Molecular Formula of Fotrin (CAS NO.37132-72-2 ) : C14H28N9OP3
Following is the structure of Fotrin (CAS NO.37132-72-2 ) :
 

FOTRIN Toxicity Data With Reference

1.    

mma-sat 1 g/plate

    PCJOAU    Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. 12 (1978),35.
2.    

cyt-hmn:lym 20 mg/L/1H

    SOGEBZ    Soviet Genetics. Translation of GNKAA5. 12 (1976),1552.
3.    

sce-hmn:lym 5 mg/L

    TGANAK    Tsitologiya i Genetika. 16 (2)(1982),34.
4.    

sce-ham:oth 125 µg/L

    CYGEDX    Cytology and Genetics. English Translation of Tsitologiya i Genetika. 16 (4)(1982),23.
5.    

sce-ham:oth 125 mg/L

    GNKAA5    Genetika. 19 (1983),1152.

FOTRIN Consensus Reports

EPA Genetic Toxicology Program.

FOTRIN Safety Profile

Experimental teratogenic effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and POx.

FOTRIN Specification

The classification code of Fotrin (CAS NO.37132-72-2 ) are alkylating agents, antineoplastic agents, antineoplastic agents, alkylating, mutagens, mutation data, noxae, reproductive effect.

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