- Efficient Synthesis of Acyclic Nucleosides by N-Alkylation of Pyrimidine and Purine-bases Using a New Coupling Agent of Cesium Iodide
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Acyclic nucleosides, ((1,3-bis(benzyloxy)-2-propoxy) methyl)-2-thio-pyrimidine, -uracil, -2-thiouracil, and -2-thioadenine, and (2-acetoxyethoxy methyl)-2-thioadenine, -2-thiopyrimidine, -uracil, and -2-thiouracil have been successfully synthesized in goo
- Kim, Yong Hae,Kim, Joong Young,Lee, Chun Ho
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p. 1045 - 1048
(2007/10/02)
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- FACILE SYNTHESIS OF ACYCLIC NUCLEOSIDES USING A NEW COUPLING AGENT OF ZINC IODIDE
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((1,3-Bis(benzyloxy)-2-propoxy)methyl)-2-thiopyrimidine-, uracil-, 2-thiouracil-, and 2-thioadenine- acyclic nucleosides and (2-acetoxyethoxy methyl)-2-thioadenine-, 2-thiopyrimidine-, uracil-, and 2-thiouracil- acyclic nucleosides have been successfully synthesized in good yields by N-alkylation using a new Lewis acid, zinc iodide in dimethylformamide.
- Kim, Yong Hae,Kim, Joong Young
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- Acyclic analogues of 2'-deoxynucleosides related to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine as potential antiviral agents
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A series of acyclic analogues of 2'-deoxynucleosides related in structure to 9-[(1,3-dihydroxy-2-propoxy)methyl]guanine (DHPG) have been synthesized and evaluated for antiviral activity against herpes simplex virus type 1 (F strain). Additionally, the abi
- Martin,Jeffrey,McGee,Tippie,Smee,Matthews,Verheyden
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p. 358 - 362
(2007/10/02)
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