cas 6958-73-2, 5-methylsulfanyl-2,4,9-triazabicyclo[4.3.0]nona-2,4,7,10-tetraene | Articles data ｜lookchem

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6958-73-2

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6-Oxo and 6-thio purine analogs as antimycobacterial agents
6-Oxo and 6-thio analogs of purine were prepared based on the initial activity screening of a small, diverse purine library against Mycobacterium tuberculosis (Mtb). Certain 6-oxo and 6-thio-substituted purine analogs described herein showed moderate to good inhibitory activity. N 9-substitution apparently enhances the anti-mycobacterial activity in the purine series described herein. Several 2-amino and 2-chloro purine analogs were also synthesized that showed moderate inhibitory activity against Mtb.
Pathak, Ashish K.,Pathak, Vibha,Seitz, Lainne E.,Suling, William J.,Reynolds, Robert C.
p. 1685 - 1695
(2013/05/09)

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Chemical Properties

Boiling Point: 363.5 °C at 760 mmHg
Flash Point:173.7 °C
Density: 1.37 g/cm³
Vapor Pressure: 2.26E-11mmHg at 25°C
Refractive Index: 1.67
PSA: 66.87000
LogP: 1.67980

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