- Experimental and theoretical investigation of the reaction of secondary amines with maleic anhydride
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The reaction of secondary amines, namely 1-methylpiperazine, pyrrolidine, morpholine, 2-methylpiperidine, and diethylamine, with maleic anhydride has been investigated experimentally and theoretically at the DFT level. Under kinetic control, i.e. at -78°C
- Kour, Manjinder,Gupta, Raakhi,Bansal, Raj K.
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p. 1247 - 1253
(2017/11/27)
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- A rapid and simple amine-catalyzed microwave-assisted isomerization of maleamides into fumaramides
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An improved, efficient, and simple method for the synthesis of nonsymmetrical diamides of fumaric acid is reported. Starting from commercially available substrates, maleic diamides are formed in two steps, and then isomerized in a focused microwave reactor in acetonitrile as the solvent in the presence of a catalytic amount of piperidine, giving the corresponding fumaramides in high yields and purity.
- Majce, Vita,Ko?evar, Marijan,Polanc, Slovenko
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supporting information; experimental part
p. 3287 - 3290
(2011/06/28)
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- Novel α-amino-acid phenolic ester derivatives with intravenous anaesthetic activity
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A novel series of α-amino-acid phenolic ester derivatives containing sulphide, sulphoxide, sulphone, ester and amide side chains were prepared and shown to display potent intravenous anaesthetic activity.
- Cooke, Andrew,Anderson, Alison,Bennett, Jonathan,Buchanan, Kirsteen,Gemmell, David,Hamilton, Niall,Maidment, Maurice,McPhail, Petula,Stevenson, Donald,Sundaram, Hardy
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p. 1107 - 1110
(2007/10/03)
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