cas 5002-38-0, (3'-Fluoro-biphenyl-4-yl)-acetic acid | Articles data ｜lookchem

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5002-38-0

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THIAZOLOPIPERAZINE DERIVATIVES AND COMPOSITION FOR PREVENTING OR TREATING AUTOIMMUNE DISEASES COMPRISING THE SAME
The present invention provides a thiazolopiperazine derivative, and a pharmaceutical composition and a health functional food composition for preventing or treating autoimmune diseases containing the same as an active component. A compound represented by chemical formula 1 or a pharmaceutically acceptable salt thereof according to the present invention can have an effect of inhibiting lysophosphatidic acid 1 (LPA1) receptor activation, thereby being able to be usefully used as the pharmaceutical composition or the health functional food composition for preventing or treating LPA1-related diseases. In addition, it is possible to effectively prevent or treat not only autoimmune diseases, but also other immune-related diseases with similar mechanisms of occurrence by using the pharmaceutical composition and the health functional food composition.COPYRIGHT KIPO 2020
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Paragraph 0118-0124; 0131; 0132

(2020/04/01)

Compositions and methods of treating cell proliferation disorders
The invention relates to compounds and methods for treating cell proliferation disorders.
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Page/Page column 75

(2008/06/13)

Aryl-aryl cross coupling on a solid support using zinc organic reagents and palladium catalysis
Aryl zinc bromides undergo palladium catalyzed coupling reactions to aryl bromides which are bound to a polystyrene resin via an ester linkage. Liberation of the biaryl carboxylic ester was achieved by transesterification.
Marquais, Sophie,Arlt, Michael
p. 5491 - 5494
(2007/10/03)

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Chemical Properties

Boiling Point: 390.7 °C at 760 mmHg
Flash Point:190.1 °C
Density: 1.235 g/cm³
Storage Temp.:2-8°C
Refractive Index: 1.579
PSA: 37.30000
LogP: 3.11980

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