cas 4402-32-8, 1-DIETHYLAMINO-2-PROPANOL | Articles data

Articles about 4402-32-8Total 10 be found

A preparation method of promethazine hydrochloride (by machine translation)
The invention discloses a method for preparation of promethazine hydrochloride, to diethyl amine and the epoxy propane to obtain the 1 - diethyl amino - 2 - propanol, then 1 - diethyl amino - 2 - propanol adds the chlorination sulfoxide, toluene to obtain the 1 - diethyl amino - 2 - chloro propane, and then the phenothiazine to obtain the ine crude free body, ine the crude free acceptor promethazine purified crude free acceptor with the hydrochloric acid salt making promethazine hydrochloride. The invention preparation of promethazine hydrochloride good quality, high yield, the preparation method is simple, low energy consumption, low cost. (by machine translation)
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Paragraph 0020; 0021

(2017/06/02)

Tetragonal versus hexagonal: Structure-dependent catalytic activity of Co/Zn bimetallic metal-organic frameworks
Tetragonal and hexagonal phases of monometallic Zn and bimetallic Co/Zn metal-organic frameworks (MOFs), with secondary building units (SBUs) containing a M3O (M = metal) cluster, were synthesized from identical constituents using a benzenetricarboxylate (BTC3-) linker that forms decorated 3,6- and 3,5-connected networks, respectively. There exist subtle differences between the SBUs; one of the metal atoms in the M3O cluster in the tetragonal phase has one dissociable DMF solvent molecule while that in the hexagonal phase has three. Connectivities between the SBUs form one-dimensional channels in both MOFs. These MOFs catalyze the chemoselective addition of amines to epoxides, giving exclusively β-hydroxyamine under heterogeneous conditions. A ring-opening reaction of a symmetrical epoxide showed that the hexagonal phase diastereoselectively yields trans-alcohol, exhibiting an exquisite model for structure-dependent activity.
Pariyar, Anand,Asl, Hooman Yaghoobnejad,Choudhury, Amitava
supporting information
p. 9250 - 9257
(2016/09/28)

Regioselective ring opening in epoxides under the action of amines in water medium
Amino(bis-amino)derivatives of 2-propanol were synthesized by ring opening in epoxides under the action of amines in water medium using environmentally safe methods. The structure of the compounds obtained was established by elemental analysis and the IR, 1H and 13C NMR spectroscopy. It was found that these substances are effective bactericides. They suppress the growth of the sulfate-reducing bacteria and exhibit high anticorrosive properties.
Talybov,Abbasov,Mamedbeili,Kochetkov
experimental part
p. 1819 - 1824
(2011/02/24)

The reaction of carbonyldiimidazole with alcohols to form carbamates and N-alkylimidazoles
The reactions of non-benzylic primary and secondary aliphatic alcohols with carbonyldiimidazole (CDI) afford the corresponding carbamates but not N-alkylimidazoles. For benzylic primary alcohols, formation of N-alkylimidazoles proceeds reasonably at 170 °C in several different solvents and occurs by way of the initially formed carbamate. However, under these rather forcing conditions, or even at lower reaction temperatures, elimination is a significant side reaction for benzylic secondary alcohols with β-hydrogen atoms. With one exception, reactions of six N,N-disubstituted β-aminoalcohols with CDI to form N-alkylimidazoles proceed under relatively mild conditions and may occur by way of an aziridinium intermediate.
Tang, Yuanqing,Dong, Yuxiang,Vennerstrom, Jonathan L.
p. 2540 - 2544
(2007/10/03)

Metal salts as new catalysts for mild and efficient aminolysis of oxiranes
A new, simple, efficient, inexpensive, anti stereoselective, highly regioselective method for aminolysis of 1,2-epoxides, by means of metal salts, is described.
Chini,Crotti,Macchia
p. 4661 - 4664
(2007/10/02)

TETRAPHENYLSTIBONIUM TRIFLATE AS A REGIO- AND CHEMOSELECTIVE CATALYST IN THE REACTION OF OXIRANES WITH AMINES
Tetraphenylstibonium triflate catalytically promotes the nucleophilic addition of amines to oxiranes under mild conditions, giving the corresponding β-amino alcohols regio- and chemoselectively.
Fujiwara, Masahiro,Imada, Makoto,Baba, Akio,Matsuda, Haruo
p. 739 - 742
(2007/10/02)

AMINOLEAD COMPOUNDS AS A NEW REAGENT FOR REGIOSELECTIVE RING OPENING OF EPOXIDES
Regioselective ring opening of epoxides is accomplished by using aminolead compounds; the reagents attack the less hindered carbon of epoxide ring, and the amino alcohols are obtained in good yields.
Yamada, Jun-ichi,Yumoto, Masatoshi,Yamamoto, Yoshinori
p. 4255 - 4258
(2007/10/02)

Fixation and Activation of Carbon Dioxide on Aluminum Porphyrin. Catalytic Formation of Carbamic Ester from Carbon Dioxide, Amine, and Epoxide
Carbon dioxide is trapped by (5,10,15,20-tetraphenylporphinato)aluminum acetate in the presence of a secondary amine in the form of an aluminum carbamate on the opposite side to the acetate group with respect to the porphyrin plane.Carbon dioxide thus trapped by aluminum porphyrin is activated enough to undergo a catalytic reaction involving secondary amine and epoxide to afford dialkylcarbamic ester under atmospheric pressure at room temperature.
Kojima, Fumitoshi,Aida, Takuzo,Inoue, Shohei
p. 391 - 395
(2007/10/02)

Regiospecific Conversion of Oxiranes, Oxetanes, and Lactones into Difunctional Nitrogen Compounds via Aminosilanes and Aminostannanes
The insertion reactions of diethylaminotrimethylsilane (TMSDEA) and diethylaminotrimethylstannane (TMSnDEA) into oxirane, oxetane, and lactone rings are reported.Regioisomerically pure β- and γ-amino alcohols were obtained, with AlCl3 or Et2AlCl catalysis, from monoalkyloxiranes and monoalkyl- and aryl-oxetanes respectively, whereas, in the majority of cases, reactions involving polysubstituted oxiranes resulted in a loss of regoiselectivity.Ring-opening reactions of the lactone rings with TMSDEA led, on the other hand, to β-amino acids or to ω-hydroxyamides depending upon the ring size.With TMSnDEA, spontaneous ring cleavage of the alkyloxiranes and β-propiolactone occurred with reversed regioselectivity, while the oxetanes and γ- and δ-lactones were opened with the same regiochemistry as that found with TMSDEA for the same ring systems.
Papini, Annamaria,Ricci, Alfredo,Taddei, Maurizio,Seconi, Giancarlo,Dembech, Pasquale
p. 2261 - 2266
(2007/10/02)