Synthesis of fluorinated pyrrolo[2,3-b]pyridine and pyrrolo[2,3-d] pyrimidine nucleosides
With the purpose of synthesizing novel ADAs (adenosine deaminase) and IMPDH (inosine 5′-monophosphate dehydrogenase) inhibitors the reactions of 5-amino-1-tert-butyl-1-H-pyrrole-3-carbonitrile with fluorinated 1,3 - bielectrophiles were studied. An effici
Iaroshenko, Viktor O.,Wang, Yan,Sevenard, Dmitri V.,Volochnyuk, Dmitriy M.
experimental part
p. 1851 - 1857
(2010/01/16)
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